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Titolo:
Efficacy and safety of zaleplon at peak plasma levels
Autore:
Mangano, RM;
Indirizzi:
Wyeth Ayerst Res, Clin Res & Dev, Radnor, PA 19087 USA Wyeth Ayerst Res Radnor PA USA 19087 Clin Res & Dev, Radnor, PA 19087 USA
Titolo Testata:
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
, , anno: 2001, supplemento:, 116
pagine: 9 - 13
SICI:
1368-5031(200101):<9:EASOZA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
ZOLPIDEM; PLACEBO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Mangano, RM Wyeth Ayerst Res, Clin Res & Dev, Radnor, PA 19087 USA Wyeth Ayerst Res Radnor PA USA 19087 ev, Radnor, PA 19087 USA
Citazione:
R.M. Mangano, "Efficacy and safety of zaleplon at peak plasma levels", INT J CL PR, 2001, pp. 9-13

Abstract

Zaleplon is a non-benzodiazepine sleep medication that shows efficacy as asleep inducer comparable to that of other hypnotics but with significantlyfewer residual effects. In addition, evaluations of psychomotor or memory function at zaleplon peak plasma levels show much less impairment than noted with other hypnotics, suggesting an improved benefit-to-risk profile for zaleplon compared with older available agents. Thus, zaleplon can be used to treat symptoms of insomnia when they occur without the concern of next-day psychomotor or memory impairment, whether administered at bedtime or later during the night. Such an approach permits physicians to reformulate their strategies for safe and effective management of sleeplessness.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 11:55:14