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Titolo:
Evaluation of two processed EEG analyzers for assessment of sedation aftercoronary artery bypass grafting
Autore:
Walder, B; Suter, PM; Romand, JA;
Indirizzi:
Univ Hosp Geneva, Dept APSIC, Div Surg Intens Care, CH-1211 Geneva 14, Switzerland Univ Hosp Geneva Geneva Switzerland 14 e, CH-1211 Geneva 14, Switzerland
Titolo Testata:
INTENSIVE CARE MEDICINE
fascicolo: 1, volume: 27, anno: 2001,
pagine: 107 - 114
SICI:
0342-4642(200101)27:1<107:EOTPEA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTENSIVE-CARE UNIT; CRITICALLY ILL PATIENTS; BISPECTRAL INDEX; MECHANICAL VENTILATION; AGITATION SCALE; PROPOFOL; MIDAZOLAM; ELECTROENCEPHALOGRAM; ANESTHESIA; SURGERY;
Keywords:
bispectral analysis; critically ill adult patients; hypnotics; sedation scoring; spectral edge frequency;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Walder, B Univ Hosp Geneva, Dept APSIC, Div Surg Intens Care, 24 Rue Micheli du Crest, CH-1211 Geneva 14, Switzerland Univ Hosp Geneva 24 Rue Michelidu Crest Geneva Switzerland 14
Citazione:
B. Walder et al., "Evaluation of two processed EEG analyzers for assessment of sedation aftercoronary artery bypass grafting", INTEN CAR M, 27(1), 2001, pp. 107-114

Abstract

Objectives: Processed EEG monitoring has been suggested for sedation depthevaluation in intensive care unit (ICU) patients. The present study investigated the efficacy of two processed EEG monitors using SEF90% or SEF95% and BIS to differentiate between conscious (Ramsay score 4) and unconscious sedation (Ramsay score 6). Design and setting: Prospective, randomized trial in a surgical ICU of a university teaching hospital. Patients: Patients recovering from elective coronary bypass grafting. Intervention: One of two EEG analyzers was installed (A: Aspect A-1000 measuring SEF95% and BIS; D: Drager pEEG measuring SEF90%). At ICU admission unconscious sedation (Ramsay score 6), and at three 30-min intervals conscious sedation (Ramsay score 4) were investigated. Measurements and results: Fourteen patients were monitored by A and 14 by D. The interindividual variability (coefficient of variation 32-69%) was large for all three processed EEG methods. SEF90% of analyzer D and BIS of analyzer A showed a statistically significant difference between unconscious and conscious sedation (11 +/- 3 and 17 +/- 6 Hz, p = 0.005; 74 +/- 10 and 83 +/- 10,p = 0.02). Positive and negative predictive values for SEF90% of analyzer D (0.57, 95% CI 0.34-0.77; and 0.92, 95% CI 0.64-0.99) and BIS of analyzer A (0.55, 95% CI 0.32-0.76; and 0.87, 95% CI 0.60-0.98) were too low for discrimination between conscious and unconscious sedation. Conclusions: The use of processed EEG monitoring cannot be recommended forassessing sedation depth after cardiac surgery.

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Documento generato il 06/04/20 alle ore 08:16:18