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Titolo:
A short note on micronucleoli in the course of terminal maturation of human erythroblasts
Autore:
Smetana, K; Jiraskova, I; Smetana, K; Cermak, J;
Indirizzi:
Inst Hematol & Blood Transfus, Clin Dept, CR-12820 Prague 2, Czech Republic Inst Hematol & Blood Transfus Prague Czech Republic 2 2, Czech Republic Charles Univ, Fac Med 1, Dept Anat, Prague, Czech Republic Charles Univ Prague Czech Republic 1, Dept Anat, Prague, Czech Republic
Titolo Testata:
FOLIA BIOLOGICA
fascicolo: 1, volume: 47, anno: 2001,
pagine: 14 - 17
SICI:
0015-5500(2001)47:1<14:ASNOMI>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
NUCLEOLUS ORGANIZER REGIONS;
Keywords:
micronucleoli; human erythroblasts; terminal differentiation; RNA staining and silver reaction for AgNOR; proteins;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Smetana, K Inst Hematol & Blood Transfus, Clin Dept, U Nemocnice 1, CR-12820 Prague 2, Czech Republic Inst Hematol & Blood Transfus U Nemocnice 1 Prague Czech Republic 2
Citazione:
K. Smetana et al., "A short note on micronucleoli in the course of terminal maturation of human erythroblasts", FOL BIOL, 47(1), 2001, pp. 14-17

Abstract

The incidence of micronucleoli in the course of terminal differentiation of human erythroblasts was studied by the cytochemical procedures for demonstration of RNA and characteristic proteins of interphase AgNORs. The last dividing stages of the erythroid lineage - polychromatophylic erythroblasts - characterized by the presence of micronucleoli exhibited significantly larger values of the nucleolar coefficient in specimens stained for AgNOR proteins than in those stained for RNA. In addition, both these and terminal non-dividing nucleated stages of the erythroid lineage - orthochromatic erythroblasts - possessed micronucleoli after staining for RNA in a much smaller percentage of cells than after staining for AgNOR proteins. Thus, both these observations indicate that micronucleoli in the course of terminal maturation of erythroblasts apparently lose the nucleolar RNA detectable by thelight microscopic cytochemistry. In addition, silver-stained micronucleoli- nucleolar remnants - were also noted in erythroblasts expelling the nucleus.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 13:10:29