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Titolo:
An unusual cause of biliary stricture in a patient with neurofibromatosis type 1
Autore:
Taylor, MA; Loughrey, MB; Toner, PG; Regan, MC;
Indirizzi:
Queens Univ Belfast, Inst Clin Sci, Dept Surg, Belfast BT12 6BJ, Antrim, North Ireland Queens Univ Belfast Belfast Antrim North Ireland BT12 6BJ , North Ireland
Titolo Testata:
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
fascicolo: 2, volume: 13, anno: 2001,
pagine: 199 - 201
SICI:
0954-691X(200102)13:2<199:AUCOBS>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
INVOLVEMENT; DISEASE;
Keywords:
biliary stricture; neurofibromatosis; von Recklinghausen's disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Taylor, MA Queens Univ Belfast, Inst Clin Sci, Dept Surg, Royal Victoria Hosp, Grosvenor Rd, Belfast BT12 6BJ, Antrim, North Ireland Queens Univ Belfast Grosvenor Rd Belfast Antrim North Ireland BT12 6BJ
Citazione:
M.A. Taylor et al., "An unusual cause of biliary stricture in a patient with neurofibromatosis type 1", EUR J GASTR, 13(2), 2001, pp. 199-201

Abstract

The majority of biliary strictures occur as a consequence of iatrogenic injury to the extrahepatic biliary tract, with more than 80% following cholecystectomy. The laparoscopic era has led to heightened awareness of this problem. The occurrence of an iatrogenic stricture can be particularly devastating to both patient and surgeon. The literature highlights a number of factors involved in the aetiology of such traumatic stricture formation. We report an unusual case of a Bismuth 2 stricture of the proximal common hepatic duct,occurring in a patient with type 1 neurofibromatosis, following an iatrogenic bile duct injury that occurred during a laparoscopic cholecystectomy, Histological examination of the strictured region of bile duct removed at surgery demonstrated multiple neurofibromas of varying sizes present in the submucosa. Neurofibromatosis type 1 (von Recklinghausen disease) affects the gastrointestinal tract in up to 25% of cases, and in such cases is characterized bymultiple submucosal neurofibromas. We believe this is the first reported case of a biliary stricture in a patient with neurofibromatosis type 1, which appeared to be as a consequence of neurofibromas in the submucosa of the bile duct. Eur J Gastroenterol Hepatol 13:199-201 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:00:37