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Titolo:
Expression of group I and II metabotropic glutamate receptors in trigeminal neurons during postnatal development
Autore:
Turman, JE; Hiyama, L; Castillo, M; Chandler, SH;
Indirizzi:
Univ So Calif, Dept Biokinesiol & Phys Therapy, Los Angeles, CA 90089 USA Univ So Calif Los Angeles CA USA 90089 Therapy, Los Angeles, CA 90089 USA Univ Calif Los Angeles, Dept Physiol Sci, Los Angeles, CA USA Univ Calif Los Angeles Los Angeles CA USA ysiol Sci, Los Angeles, CA USA
Titolo Testata:
DEVELOPMENTAL NEUROSCIENCE
fascicolo: 1, volume: 23, anno: 2001,
pagine: 41 - 54
SICI:
0378-5866(200101/02)23:1<41:EOGIAI>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; RAT-BRAIN; MESSENGER-RNA; MESENCEPHALIC NUCLEUS; SIGNAL TRANSDUCTION; GUINEA-PIG; IMMUNOHISTOCHEMICAL LOCALIZATION; MASSETER MUSCLE; ORAL BEHAVIOR; MOTOR NUCLEUS;
Keywords:
glutamate; immunohistochemistry; jaw; suckling;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
68
Recensione:
Indirizzi per estratti:
Indirizzo: Turman, JE Univ So Calif, Dept Biokinesiol & Phys Therapy, 1540 E Alcazar St,CHP155, Los Angeles, CA 90089 USA Univ So Calif 1540 E Alcazar St,CHP155Los Angeles CA USA 90089
Citazione:
J.E. Turman et al., "Expression of group I and II metabotropic glutamate receptors in trigeminal neurons during postnatal development", DEV NEUROSC, 23(1), 2001, pp. 41-54

Abstract

Trigeminal motoneurons (Mo5), mesencephalic trigeminal neurons (Me5), supratrigeminal neurons (Su5), and intertrigeminal neurons (I5) are important constituents of the neural circuitry responsible for jaw movements. Glutamate neurotransmission, mediated by ionotropic and metabotropic glutamate receptors (mGluRs), is critical for the production of jaw movements. To better understand the role of mGluR-mediated modulation of these neurons during early postnatal development, we conducted a series of experiments to illustrate the ontogeny of mGluRs 1, 5 (group I) and mGluRs 2, 3 (group II) in Mo5,Me5, Su5, and 15 neurons using receptor immunohistochemistry. Results demonstrate that the temporal expression of mGluRs is differentially regulated between, and within these trigeminal nuclei. The localization of group I and II mGluRs in these nuclei suggests a role for these receptors in mediating glutamatergic neurotransmission in brainstem circuits responsible for oral-motor behaviors. Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 11:23:40