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Titolo:
Epidemiology of psychiatric medication use in patients recovering from critical illness at a long-term acute-care facility
Autore:
Weinert, CR;
Indirizzi:
Univ Minnesota, Dept Med, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 pt Med, Minneapolis, MN 55455 USA
Titolo Testata:
CHEST
fascicolo: 2, volume: 119, anno: 2001,
pagine: 547 - 553
SICI:
0012-3692(200102)119:2<547:EOPMUI>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ISCHEMIC-HEART-DISEASE; MEDICALLY ILL PATIENTS; ELDERLY PATIENTS; DOUBLE-BLIND; INTENSIVE-CARE; COST-OFFSET; DEPRESSION; METHYLPHENIDATE; ANTIDEPRESSANTS; NORTRIPTYLINE;
Keywords:
antidepressants; benzodiazepines; critical illness; mechanical ventilation; pharmacoepidemiology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Weinert, CR Univ Minnesota, Dept Med, MMC 276 Mayo,420 Delaware St SE, Minneapolis, MN55455 USA Univ Minnesota MMC 276 Mayo,420 Delaware St SE Minneapolis MN USA 55455
Citazione:
C.R. Weinert, "Epidemiology of psychiatric medication use in patients recovering from critical illness at a long-term acute-care facility", CHEST, 119(2), 2001, pp. 547-553

Abstract

Study objectives: To describe the pharmacoepidemiology of psychotropic medication prescription in patients recovering from life-threatening medical and surgical illness. Design: Retrospective analysis of a random sample of medical records. Setting: Regional referral center. Patients: Eighty-nine randomly selected patients transferred from an ICU to the study facility. Interventions: None. Measurements and results: Patients had been treated at the referring ICU for 33 +/- 24 days (mean +/- SD) and remained at the study hospital for 64 +/- 52 days. Most of the patients had prolonged respiratory failure. Nearly half of the patients (47%) received an antidepressant medication while at the facility, and 48% received at least one dose of a benzodiazepine on the first day after transfer. In the sample of 75 patients not prescribed an antidepressant before transfer, 37% were started on therapy with an agent, usually within 3 weeks and predominantly in the selective serotonin reuptake inhibitor or psychostimulant class. Younger patients and those evaluated bya mental health specialist were more likely to be prescribed an antidepressant, compared to other patients. Forty percent of patients were still receiving at least one dose of a benzodiazepine in a 24-h period after their third week at the facility. Conclusion: Although the efficacy of antidepressant pharmacotherapy in patients with comparable severity of medical illness has not been established,a substantial proportion of patients recovering from critical illness at aspecialized facility are prescribed antidepressant medications. Benzodiazepine exposure is frequent after transfer, and the prevalence in patients who remain at the facility minimally decreases over time.

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Documento generato il 22/01/20 alle ore 22:16:05