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Titolo:
The neuropsychopharmacology of criminality and aggression
Autore:
Lee, R; Coccaro, E;
Indirizzi:
Univ Chicago, Dept Psychiat, Clin Neurosci & Psychopharmacol Res Unit, Chicago, IL 60637 USA Univ Chicago Chicago IL USA 60637 armacol Res Unit, Chicago, IL 60637 USA
Titolo Testata:
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
fascicolo: 1, volume: 46, anno: 2001,
pagine: 35 - 44
SICI:
0706-7437(200102)46:1<35:TNOCAA>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBROSPINAL-FLUID MONOAMINE; POSITRON-EMISSION-TOMOGRAPHY; D-FENFLURAMINE CHALLENGE; HEALTHY-HUMAN SUBJECTS; ANTISOCIAL PERSONALITY-DISORDER; HABITUALLY VIOLENT OFFENDERS; TRYPTOPHAN-HYDROXYLASE GENE; MALE CYNOMOLGUS MACAQUES; GLUCOSE-TOLERANCE TEST; PROLACTIN RESPONSE;
Keywords:
aggressive; serotonin; 5-HIAA; fenfluramine; impulsiveness; criminality; pharmacochallenge;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
111
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, R Univ Chicago, Dept Psychiat, Clin Neurosci & Psychopharmacol Res Unit, 5841 S Maryland Ave,MC 3077, Chicago, IL 60637 USA Univ Chicago 5841 S Maryland Ave,MC 3077 Chicago IL USA 60637 7 USA
Citazione:
R. Lee e E. Coccaro, "The neuropsychopharmacology of criminality and aggression", CAN J PSY, 46(1), 2001, pp. 35-44

Abstract

Although the idea that aggression has biological components is not a new one, recent research in genetics, neuropsycharmacology and neuroimaging has helped clarify the biological contributions to aggression. Studies to date have focused on serotonergic function and impulsive aggression. Reduced levels of cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5-HIAA) are associated with impulsive aggression. Pharmacochallenge studies have found decreased serotonergic responsiveness associated with impulsive aggression. Neuroimaging studies suggest a role for the prefrontal cortex, along with other regions of the brain, in the expression of aggression. Serotonin is notthe only aspect of brain function implicated in impulsive aggression, and further work is being done on other neurotransmitters and neuropeptides.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/01/20 alle ore 19:00:44