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Titolo:
Illness characteristics and their association with prescription patterns for bipolar I disorder
Autore:
Levine, J; Chengappa, KNR; Brar, JS; Gershon, S; Kupfer, JD;
Indirizzi:
Western Psychiat Inst & Clin, Stanley Ctr Innovat Treatment Bipolar Disorder, Pittsburgh, PA 15213 USA Western Psychiat Inst & Clin Pittsburgh PA USA 15213 sburgh, PA 15213 USA Univ Pittsburgh, Sch Med, Western Psychiat Inst & Clin, Pittsburgh, PA 15260 USA Univ Pittsburgh Pittsburgh PA USA 15260 & Clin, Pittsburgh, PA 15260 USA Mayview State Hosp, Special Studies Ctr, Bridgeville, PA 15017 USA MayviewState Hosp Bridgeville PA USA 15017 tr, Bridgeville, PA 15017 USA
Titolo Testata:
BIPOLAR DISORDERS
fascicolo: 1, volume: 3, anno: 2001,
pagine: 41 - 49
SICI:
1398-5647(200102)3:1<41:ICATAW>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUICIDE RISK; LITHIUM; CARBAMAZEPINE; THERAPY; MANIA; ONSET; AGE;
Keywords:
activities of daily living; age at onset; automobile driving; bipolar disorder; demography; employment; polypharmacy; psychopharmacology; suicide;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Chengappa, KNR Western Psychiat Inst & Clin, Stanley Ctr Innovat TreatmentBipolar Disorder, 3811 OHara St, Pittsburgh, PA 15213 USA Western PsychiatInst & Clin 3811 OHara St Pittsburgh PA USA 15213
Citazione:
J. Levine et al., "Illness characteristics and their association with prescription patterns for bipolar I disorder", BIPOL DIS, 3(1), 2001, pp. 41-49

Abstract

Introduction: The present study explores the relationships among psychotropic medications, illness-related parameters, patient demography, suicidality, and levels of functioning in a voluntary bipolar case registry. Methods: Four. hundred and fifty-seven subjects with bipolar T disorder were selected from a voluntary registry for subjects with bipolar illness. Demographic characteristics, psychotropic medications, age at onset of illness, duration of illness, number of hospitalizations, the ability to live independently, employment and driving status as well as the history of suicidal attempts were obtained through a structured phone interview. Results: subjects treated with antidepressants had a shorter duration of illness, while patients treated with antipsychotic drugs had an earlier onset of illness. The number of hospitalizations for mania was fewer among patients takings a combination of lithium and carbamazepine as compared to patients not receiving them, while subjects taking neuroleptics had more hospitalizations as compared to subjects not receiving them. The number of psychotropic agents prescribed correlated positively with the number of hospitalizations For depressive episodes. Curiously, no correlations were found between the types of psychotropic agents prescribed and the levels of functioning or a history of suicidal attempts. Interestingly, our results suggest that more than half of the subjects were unable to live independently or to work due to their illness. Also, more than 50% of the subjects had at least one suicidal attempt, the majority occurred during depressive episodes. Conclusions: Our results suggest that subjects with bipolar I disorder have high rate of suicidal attempts and may have serious functional impairments.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 13:03:12