Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Increase in plasma levels of oxidized low-density lipoproteins in patientswith coronary spastic angina
Autore:
Kugiyama, K; Sugiyama, S; Soejima, H; Kawano, H; Sakamoto, T; Takazoe, K; Ogawa, H; Doi, H; Yasue, H;
Indirizzi:
Kumamoto Univ, Sch Med, Dept Cardiovasc Med, Kumamoto 8608556, Japan Kumamoto Univ Kumamoto Japan 8608556 iovasc Med, Kumamoto 8608556, Japan
Titolo Testata:
ATHEROSCLEROSIS
fascicolo: 2, volume: 154, anno: 2001,
pagine: 463 - 467
SICI:
0021-9150(20010201)154:2<463:IIPLOO>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTERIAL SPASM; VITAMIN-C; ATHEROSCLEROSIS; PATHOGENESIS; OXIDATION; DEFICIENT;
Keywords:
vasospasm; lipoproteins; acetylcholine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Kugiyama, K Kumamoto Univ, Sch Med, Dept Cardiovasc Med, 1-1-1 Honjo, Kumamoto 8608556, Japan Kumamoto Univ 1-1-1 Honjo Kumamoto Japan 8608556 08556, Japan
Citazione:
K. Kugiyama et al., "Increase in plasma levels of oxidized low-density lipoproteins in patientswith coronary spastic angina", ATHEROSCLER, 154(2), 2001, pp. 463-467

Abstract

Oxidized low-density lipoproteins (LDL) impair endothelium-dependent dilation and constrict arteries. This study examined possible relation of the circulating plasma levels of Ox-LDL to coronary spastic angina (CSA). The plasma levels of Ox-LDL were measured by ELISA in 37 consecutive patients withCSA and normal coronary angiograms and in 79 consecutive control patients. The Ox-LDL levels in patients with CSA were significantly higher than those in controls. In multivariate analysis, higher levels of Ox-LDL were a risk factor for CSA independently of other traditional risk factors. The Ox-LDL, levels had a significant and positive correlation with constrictor response of coronary arteries to the intracoronary acetylcholine infusion. Thus,Ox-LDL may play a possible role in pathogenesis of coronary spasm. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:54:50