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Titolo:
ASSESSING PATTERNS OF AGITATION IN ALZHEIMERS-DISEASE PATIENTS WITH THE COHEN-MANSFIELD AGITATION INVENTORY
Autore:
KOSS E; WEINER M; ERNESTO C; COHENMANSFIELD J; FERRIS SH; GRUNDMAN M; SCHAFER K; SANO M; THAL LJ; THOMAS R; WHITEHOUSE PJ;
Indirizzi:
UNIV HOSP CLEVELAND,ALZHEIMERS CTR,12200 FAIRHILL RD CLEVELAND OH 44120 CASE WESTERN RESERVE UNIV,DEPT NEUROL CLEVELAND OH 44106 UNIV TEXAS,SW MED CTR,DEPT PSYCHIAT HOUSTON TX 00000 HEBREW HOME GREATER WASHINGTON WASHINGTON DC 00000 GEORGETOWN UNIV WASHINGTON DC 00000 NYU,MED CTR,DEPT PSYCHIAT,AGING & DEMENTIA RES CTR NEW YORK NY 10016 COLUMBIA UNIV,GERTRUDE H SERGIEVSKY CTR NEW YORK NY 00000 UNIV CALIF SAN DIEGO,DEPT NEUROSCI SAN DIEGO CA 92103 UNIV CALIF SAN DIEGO,ALZHEIMERS DIS COOPERAT STUDY SAN DIEGO CA 92103
Titolo Testata:
Alzheimer disease and associated disorders
, volume: 11, anno: 1997, supplemento:, 2
pagine: 45 - 50
SICI:
0893-0341(1997)11:<45:APOAIA>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
RATING-SCALE; BEHAVIOR; DEMENTIA;
Keywords:
ALZHEIMERS DISEASE COOPERATIVE STUDY; AGITATION; ALZHEIMERS DISEASE; COHEN-MANSFIELD AGITATION INVENTORY; LONGITUDINAL CHANGES; RELIABILITY; TEMPORAL PATTERNS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
E. Koss et al., "ASSESSING PATTERNS OF AGITATION IN ALZHEIMERS-DISEASE PATIENTS WITH THE COHEN-MANSFIELD AGITATION INVENTORY", Alzheimer disease and associated disorders, 11, 1997, pp. 45-50

Abstract

As part of the effort of the NIA Alzheimer's disease cooperative study to develop improved instruments for quantifying effects in Alzheimer's disease (AD) clinical trials, patterns of agitated behaviors were evaluated with the Cohen-Mansfield Agitation Inventory (CMAI) in 241 ADpatients and 64 healthy elderly controls with valid baseline assessment on the CMAI, The test-retest reliability of the CMAI over 1 month was good (r = 0.74 to 0.92). Physically and verbally nonaggressive behaviors were most often reported, whereas physically aggressive behaviors were rare. Frequency of agitated behaviors increased with dementia severity, especially for patients with a Mini-Mental Status Exam score of 0-4. Agitation tended to increase in the evening with dementia severity for the more impaired patients. Amount of agitation did increase after 12 months in all but controls and mildly demented patients, The CMAI shows promise for evaluating a unique aspect of behavior and may be useful in assessing the effects of cognitive enhancers and other types of psychotropic drugs on behavior in dementia patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 10:36:10