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Titolo:
Baroreflex effectiveness index: an additional measure of baroreflex control of heart rate in daily life
Autore:
Di Rienzo, M; Parati, G; Castiglioni, P; Tordi, R; Mancia, G; Pedotti, A;
Indirizzi:
Fdn Don Carlo Gnocchi ONLUS, LaRC, Ctr Bioingn, I-20148 Milan, Italy Fdn Don Carlo Gnocchi ONLUS Milan Italy I-20148 gn, I-20148 Milan, Italy Politecn Milan, I-20148 Milan, Italy Politecn Milan Milan Italy I-20148Politecn Milan, I-20148 Milan, Italy Ist Sci Osped San Luca, Ist Auxol Italiano, I-20147 Milan, Italy Ist Sci Osped San Luca Milan Italy I-20147 taliano, I-20147 Milan, Italy Osped San Gerardo, Monza, Italy Osped San Gerardo Monza ItalyOsped San Gerardo, Monza, Italy Univ Milan, I-20133 Milan, Italy Univ Milan Milan Italy I-20133Univ Milan, I-20133 Milan, Italy Politecn Milan, Dipartimento Bioingn, I-20133 Milan, Italy Politecn MilanMilan Italy I-20133 timento Bioingn, I-20133 Milan, Italy
Titolo Testata:
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
fascicolo: 3, volume: 280, anno: 2001,
pagine: R744 - R751
SICI:
0363-6119(200103)280:3<R744:BEIAAM>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-PRESSURE; BARORECEPTOR REFLEX;
Keywords:
baroreceptor; blood pressure variability;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Di Rienzo, M Fdn Don Carlo Gnocchi ONLUS, LaRC, Ctr Bioingn, Via Capecelatro 66, I-20148 Milan, Italy Fdn Don Carlo Gnocchi ONLUS Via Capecelatro 66 Milan Italy I-20148
Citazione:
M. Di Rienzo et al., "Baroreflex effectiveness index: an additional measure of baroreflex control of heart rate in daily life", AM J P-REG, 280(3), 2001, pp. R744-R751

Abstract

In healthy subjects, progressive beat-to-beat increases or decreases in systolic blood pressure (SBP) ramps are not always accompanied by baroreflex-driven lengthening or shortening in pulse interval (PI) ramps, respectively. This phenomenon has been quantified by a new index, the baroreflex effectiveness index (BEI), defined as the ratio between the number of SBP ramps followed by the respective reflex PI ramps and the total number of SBP rampsobserved in a given time window. Specificity of BEI was shown in eight cats by a -89% reduction of BEI after sinoaortic denervation. In 14 healthy humans, the 24-h average BEI value was 0.21, with a marked day-night modulation (approximate to0.25 day, approximate to0.15 night) in counterphase with modulation of baroreflex sensitivity (BRS). Our analysis indicates that 1) in normal subjects, arterial baroreflex can induce beat-by-beat PI changes in response to only 21% of all SBP ramps, possibly because of central inhibitory influences or of interferences at sinus node level by nonbaroreflex mechanisms and 2) BEI provides information on the baroreflex function that is complementary to BRS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 07:46:04