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Titolo:
Effectiveness and safety of Abciximab after failed thrombolytic therapy
Autore:
Cantor, WJ; Kaplan, AL; Velianou, JL; Sketch, MH; Barsness, GW; Berger, PB; Ohman, EM;
Indirizzi:
Duke Univ, Med Ctr, Durham, NC 27710 USA Duke Univ Durham NC USA 27710Duke Univ, Med Ctr, Durham, NC 27710 USA Mayo Clin, Rochester, MN USA Mayo Clin Rochester MN USAMayo Clin, Rochester, MN USA
Titolo Testata:
AMERICAN JOURNAL OF CARDIOLOGY
fascicolo: 4, volume: 87, anno: 2001,
pagine: 439 -
SICI:
0002-9149(20010215)87:4<439:EASOAA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; TRANSLUMINAL CORONARY ANGIOPLASTY; PLASMINOGEN-ACTIVATOR; BLEEDING COMPLICATIONS; TRIAL; ANTIBODY; BLOCKADE; OUTCOMES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Cantor, WJ Duke Univ, Med Ctr, Durham, NC 27710 USA Duke Univ Durham NC USA 27710 v, Med Ctr, Durham, NC 27710 USA
Citazione:
W.J. Cantor et al., "Effectiveness and safety of Abciximab after failed thrombolytic therapy", AM J CARD, 87(4), 2001, pp. 439

Abstract

Among 214 patients treated with abciximab within 24 hours of full-dose thrombolytic therapy, major bleeding occurred in 50 patients (23%; 95% confidence interval [Cl] 18% to 30%) and intracranial hemorrhage occurred in 3 patients (1.4%; 95% Cl 0.3% to 4%). The independent multivariate predictors ofmajor bleeding were age (odds ratio [OR] 1.53/10 years, 95% Cl 1.05 to 2.21, p = 0.03), time from thrombolytic to abciximab (OR 0.91/hour, 95% Cl 0.83 to 0.99, p = 0.03), and intra-aortic balloon pump insertion (OR 4.42, 95%Cl 2.00 to 9.72, p = 0.0002).

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Documento generato il 14/07/20 alle ore 06:09:24