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Titolo:
Transcranial doppler detection of circulating cerebral microemboli
Autore:
Reinecke, H; Nabavi, DG; Allroggen, A; Droste, DW; Breithardt, G; Ringelstein, EB;
Indirizzi:
Univ Munster, Med Klin & Poliklin Innere Med C, D-48129 Munster, Germany Univ Munster Munster Germany D-48129 ere Med C, D-48129 Munster, Germany Univ Munster, Neurol Klin & Poliklin, D-48129 Munster, Germany Univ Munster Munster Germany D-48129 Poliklin, D-48129 Munster, Germany
Titolo Testata:
ZEITSCHRIFT FUR KARDIOLOGIE
fascicolo: 1, volume: 90, anno: 2001,
pagine: 43 - 51
SICI:
0300-5860(200101)90:1<43:TDDOCC>2.0.ZU;2-B
Fonte:
ISI
Lingua:
GER
Soggetto:
PROSTHETIC CARDIAC VALVES; INTENSITY TRANSIENT SIGNALS; INTERNAL CAROTID-ARTERY; EMBOLIC SIGNALS; CARDIOPULMONARY BYPASS; ATRIAL-FIBRILLATION; ENDARTERECTOMY; ULTRASOUND; STROKE; DIFFERENTIATION;
Keywords:
microemboli; thromboembolic events; transcranial dopplersonography; risk stratification;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Reinecke, H Univ Munster, Med Klin & Poliklin Innere Med C, D-48129 Munster, Germany Univ Munster Munster Germany D-48129 -48129 Munster, Germany
Citazione:
H. Reinecke et al., "Transcranial doppler detection of circulating cerebral microemboli", Z KARDIOL, 90(1), 2001, pp. 43-51

Abstract

Thromboembolic events represent a major complication of cardiovascular diseases and interventions. Although general risk factors and predictors for thromboembolic events are well known from population-based studies, hardly any therapeutic consequences for the individual patient can be drawn, e.g. for a well-balanced therapy with anticoagulants. A new approach towards an optimised therapy adapted to the individual risk of each patient may be based on the detection of circulating microemboli by transcranial Doppler sonography. With this technique, gaseous or solid microparticles circulating in the blood can non-invasively be detected. Due to their small size, they do not induce thromboembolic events themselves. However, several studies demonstrate that they indicate an increased thromboembolic activity and correlate directly with manifest stroke or emboli. From a transcranial Doppler probe positioned on the temporal plane at the patient's skull, the middle cerebral artery's blood flow is recorded and is analysed acoustically and optically for circulating microemboli. This technique has already been used for risk stratification of highrisk patients and therapeutic decision-making in neurologic routine, e.g. for the indication to anticoagulate the patient orfor carotis surgery. Data to evaluate its value in cardiology are limited and based on few clinical studies. In this review, the basic principles andthe methodological and technical background for the detection of microemboli, as well as current limitations, are discussed. Furthermore, clinical studies and their results evaluating this technique in patients with cardiological diseases and during cardiovascular interventions are reviewed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/21 alle ore 04:06:26