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Titolo:
Exclusion of coronary calcium with electron beam computed tomography: an effective filter before diagnostic heart catheterization in symptomatic patients?
Autore:
Haberl, R; Becker, A; Lang, C; Becker, C; Knez, A; Leber, A; Bruning, R; Reiser, M; Steinbeck, G;
Indirizzi:
Univ Munich, Klinikum Grosshadern, Med Klin 1, D-81377 Munich, Germany Univ Munich Munich Germany D-81377 , Med Klin 1, D-81377 Munich, Germany Univ Munich, Inst Radiol, D-80539 Munich, Germany Univ Munich Munich Germany D-80539 Inst Radiol, D-80539 Munich, Germany
Titolo Testata:
ZEITSCHRIFT FUR KARDIOLOGIE
fascicolo: 1, volume: 90, anno: 2001,
pagine: 21 - 27
SICI:
0300-5860(200101)90:1<21:EOCCWE>2.0.ZU;2-C
Fonte:
ISI
Lingua:
GER
Soggetto:
ARTERY DISEASE; INTRACORONARY ULTRASOUND; RISK-FACTORS; CALCIFICATION; ANGIOGRAPHY; CT; ATHEROSCLEROSIS; QUANTIFICATION; SEVERITY; PREDICTION;
Keywords:
electron beam tomography; coronary calcium; cardiac catheterization;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Haberl, R Univ Munich, Klinikum Grosshadern, Med Klin 1, Marchioninistr 15, D-81377 Munich, Germany Univ Munich Marchioninistr 15 Munich Germany D-81377 h, Germany
Citazione:
R. Haberl et al., "Exclusion of coronary calcium with electron beam computed tomography: an effective filter before diagnostic heart catheterization in symptomatic patients?", Z KARDIOL, 90(1), 2001, pp. 21-27

Abstract

Electron beam computed tomography (EBCT) is the most sensitive and accurate method of measuring coronary calcium which indicates coronary atherosclerosis. We performed a prospective study in 1764 symptomatic patients who were referred to our hospital for coronary angiography because of suspected coronary artery disease. In all of these patients cardiac catheterization andcoronary calcium scanning was performed within 3.2+/-4 days.454/1225 men (37.0%) and 165/539 women (30.6%) had significant coronary stenoses greater than or equal to 75%. Only two men (0.4%) and no single woman (0.0%) with stenoses greater than or equal to 75% and only 3/323 patients(0.9%) with moderate stenoses (50-75%) did not exhibit coronary calcium. Coronary angiography excluded stenoses in 822 patients. Of these patients 261 (29.4%) did not reveal coronary calcium. In younger patients (<60 years) without stenosis exclusion of coronary calcium was a frequent finding: 31% of men and 55.8% of women were free of coronary calcium. Thus, exclusion of coronary calcium with electron beam tomography defines a substantial subgroup of patients who have an extremely low risk of significant coronary stenosis despite suspected coronary artery disease in history and non-invasive testing. Determination of coronary calcium might, therefore, be an effective filter before invasive angiography in selected groups of symptomatic patients.

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Documento generato il 05/07/20 alle ore 06:30:45