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Titolo:
Ultrasonic tissue characterization with integrated backscatter during inotropic stimulation
Autore:
Wu, C; Liu, YB; Lin, LC; Ho, YL; Liau, CS; Lee, YT;
Indirizzi:
Natl Taiwan Univ Hosp, Dept Internal Med, Cardiol Sect, Taipei 10016, Taiwan Natl Taiwan Univ Hosp Taipei Taiwan 10016 iol Sect, Taipei 10016, Taiwan
Titolo Testata:
ULTRASOUND IN MEDICINE AND BIOLOGY
fascicolo: 9, volume: 26, anno: 2000,
pagine: 1413 - 1420
SICI:
0301-5629(200011)26:9<1413:UTCWIB>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; DOBUTAMINE STRESS ECHOCARDIOGRAPHY; VENTRICULAR-FUNCTION; WALL MOTION; REPERFUSION; ISCHEMIA; ARTERY; DYSFUNCTION; OCCLUSION; VIABILITY;
Keywords:
ultrasonic backscatter; tissue characterization; inotropic stimulation; ischemic heart disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, YT Natl Taiwan Univ Hosp, Dept Internal Med, Cardiol Sect, 7 Chung Shan S Rd,Taipei 10016, Taiwan Natl Taiwan Univ Hosp 7 Chung Shan S Rd Taipei Taiwan 10016 aiwan
Citazione:
C. Wu et al., "Ultrasonic tissue characterization with integrated backscatter during inotropic stimulation", ULTRASOUN M, 26(9), 2000, pp. 1413-1420

Abstract

Ultrasonic tissue characterization with integrated backscatter is an objective method to quantitatively define the physical state of the myocardium. To determine if backscatter imaging during inotropic stimulation could be used objectively to determine the myocardial viability and ischemia in patients with isc hemic heart disease, the backscatter changes were examined in 23 patients with myocardial infarction during dobutamine stress two-dimensional (2-D) echocardiography. Coronary angiography was performed within 1 to2 days after the stress test. The results of this study demonstrated that changes in backscatter variability correlated significantly with the wall motion changes in stress echocardiography during dobutamine infusion (p < 0.0001). In addition, it was shown that the backscatter changes were significantly different in various types of myocardial tissue. In 23 healthy control segments, the ultrasonic backscatter variability was preserved and unchanged during inotropic stimulation (p = NS). In 15 viable infarct zones, restoration or an increase in backscatter variability during low-dose dobutamine infusion was noted, this being lost when ischemia developing during high-dose dobutamine infusion (p < 0.01). In 9 nonviable infarct zones, the phase-weighted variation was usually less than or equal to 0 and did not changesignificantly during inotropic stimulation, regardless of the patency of the infarct-related arteries. In 15 remote ischemic myocardial zones, the backscatter variability was preserved at the baseline level, did not change during low-dose dobutamine infusion, but decreased significantly during high-dose dobutamine stress (p < 0.01). In conclusion, dobutamine stress tissuecharacterization could offer an objective approach for the detection of myocardial viability and ischemia, and might be a useful adjunct to the conventional stress echocardiography. (C) 2001 World Federation for Ultrasound in Medicine & Biology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 10:56:35