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Titolo:
Calcium and mitosis
Autore:
Whitaker, M; Larman, MG;
Indirizzi:
Univ Newcastle Upon Tyne, Sch Med, Dept Physiol Sci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England Univ Newcastle Upon Tyne Newcastle Upon Tyne Tyne & Wear England NE2 4HH
Titolo Testata:
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
fascicolo: 1, volume: 12, anno: 2001,
pagine: 53 - 58
SICI:
1084-9521(200102)12:1<53:CAM>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEA-URCHIN EGG; NUCLEAR-ENVELOPE BREAKDOWN; INTRACELLULAR FREE CALCIUM; PHOSPHOLIPASE C-GAMMA; XENOPUS-LAEVIS BLASTOMERES; CELL-CYCLE PROGRESSION; INOSITOL TRISPHOSPHATE; ENDOPLASMIC-RETICULUM; INSP(3) RECEPTOR; MITOTIC FORCES;
Keywords:
calcium; calmodulin; mitosis; phospholipase C; sea urchin;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
66
Recensione:
Indirizzi per estratti:
Indirizzo: Whitaker, M Univ Newcastle Upon Tyne, Sch Med, Dept Physiol Sci, Framlington Pl, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England Univ Newcastle Upon Tyne Framlington Pl Newcastle Upon Tyne Tyne & Wear England NE2 4HH
Citazione:
M. Whitaker e M.G. Larman, "Calcium and mitosis", SEM CELL D, 12(1), 2001, pp. 53-58

Abstract

Calcium is thought to be involved in regulating mitotic transitions. The basis for this view is set out. Recent data from experiments on sea urchin embryos is discussed. The relative simplicity of the embryonic cell cycle and the relative ease with which cell physiology can be done in sea urchin embryos has allowed the clear demonstration that the phosphoinositide-calcium-calmodulin signalling pathway is required for and regulates mitosis entry and anaphase onset. The relevance of the sea urchin work to mitosis in other cell types is briefly discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 01:14:31