Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Subtyping schizophrenia according to outcome or severity: A search for homogeneous subgroups
Autore:
Roy, MA; Merette, C; Maziade, M;
Indirizzi:
Univ Laval Robert Giffard, Ctr Rech, Beauport, PQ G1J 2G3, Canada Univ Laval Robert Giffard Beauport PQ Canada G1J 2G3 , PQ G1J 2G3, Canada
Titolo Testata:
SCHIZOPHRENIA BULLETIN
fascicolo: 1, volume: 27, anno: 2001,
pagine: 115 - 138
SICI:
0586-7614(2001)27:1<115:SSATOO>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMA HOMOVANILLIC-ACID; LONG-TERM STABILITY; IV FIELD TRIAL; DEFICIT SYNDROME; NEGATIVE SYMPTOMS; NONDEFICIT SCHIZOPHRENIA; KRAEPELINIAN SCHIZOPHRENIA; VENTRICULAR ENLARGEMENT; SYSTEMATIC SAMPLE; ANALYTIC APPROACH;
Keywords:
schizophrenia; genetics; etiology; subtypes; deficit syndrome; congenital schizophrenia; Kraepelinian; nosology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
98
Recensione:
Indirizzi per estratti:
Indirizzo: Roy, MA Univ Laval Robert Giffard, Ctr Rech, 2601 Canardiere, Beauport, PQG1J 2G3, Canada Univ Laval Robert Giffard 2601 Canardiere Beauport PQ Canada G1J 2G3
Citazione:
M.A. Roy et al., "Subtyping schizophrenia according to outcome or severity: A search for homogeneous subgroups", SCHIZO BULL, 27(1), 2001, pp. 115-138

Abstract

There is a growing consensus that current definitions of schizophrenia (SZ) include different disorders, or else different dimensions underlain by different pathophysiologies. This article reviews the evidence for the validity of three novel strategies to subtype SZ according to outcome or severity(deficit vs, nondeficit, Kraepelinian vs. non-Kraepelinian, congenital vs.adult-onset). Medline and bibliographies were used to locate articles. Themethodology of the studies was reviewed, and their results were grouped according to seven validating criteria. Several differences were found between subtypes, particularly for the deficit/nondeficit subtypes. However, for most of these differences, replications have yet to be undertaken. Important indicators of etiology from the environmental risk factors and genetic domains have received very little attention. These three subtyping strategiesrepresent promising attempts to address the etiologic heterogeneity of SZ. However, one cannot conclude whether these strategies identify etiologically distinct SZ subgroups. We propose ten methodological and conceptual recommendations for future studies aimed at the identification of valid SZ subtypes according to outcome or severity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 18:26:35