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Titolo:
MR-tomographic characterization of suspicious breast lesions with dynamic susceptibility contrast sequences.
Autore:
Dannert, S; Kruck, W; Schick, F; Claussen, CD; Muller-Schimpfle, M;
Indirizzi:
Univ Tubingen, Abt Radiol Diagnost, D-72076 Tubingen, Germany Univ Tubingen Tubingen Germany D-72076 agnost, D-72076 Tubingen, Germany
Titolo Testata:
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
fascicolo: 1, volume: 173, anno: 2001,
pagine: 38 - 43
SICI:
1438-9029(200101)173:1<38:MCOSBL>2.0.ZU;2-P
Fonte:
ISI
Lingua:
GER
Soggetto:
ENHANCEMENT; MAMMOGRAPHY;
Keywords:
magnetic resonance imaging; breast neoplasm; perfusion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Dannert, S Univ Tubingen, Abt Radiol Diagnost, Hoppe Seyler Str 3, D-72076Tubingen, Germany Univ Tubingen Hoppe Seyler Str 3 Tubingen Germany D-72076 many
Citazione:
S. Dannert et al., "MR-tomographic characterization of suspicious breast lesions with dynamic susceptibility contrast sequences.", ROFO-F RONT, 173(1), 2001, pp. 38-43

Abstract

Purpose: To increase specificity of MR-mammography by using dynamic T-2* sequences. Methods: 23 patients with suspicious lesions of the breast underwent conventional dynamic T-1-weighted (T-1-dynamic) breast MRI and, subsequently, dynamic T-2*-weighted (T-2*-dynamic) perfusion studies. To assess the T-1-dynamic, signal enhancement during the first minute (El) was calculated. To evaluate the T-2*-dynamic, relative signal intensity loss after administration of contrast medium was determined. Results: After administrationof contrast medium. 6 of 13 malignant lesions did not show a signal decrease during the T-2*-dynamic. Two of them exhibited an atypical signal enhancement in the T-1-dynamic, with E-1 < 100%. On the other hand, in 5 of 10 benign tumors a relative signal decrease of between 5-17% occurred during theT-2*-dynamic. Four benign lesions showed a strong early signal enhancementduring the T-1-dynamic (E-1 > 100%), which is more typical for malignant lesions. Discussion: The use of dynamic T-2* sequences, following dynamic T-1-weighted breast MRI and administration of contrast medium, does not sufficiently increase diagnostic sensitivity. Thus, this study does not support the potential advantage of susceptibility MR imaging for a further characterization of breast lesions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 01:31:03