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Titolo:
Quantitative multi-slice imaging of perfusion of the brain.
Autore:
Kostler, H; Becker, H;
Indirizzi:
Univ Wurzburg, Inst Rontgendiagnost, D-97080 Wurzburg, Germany Univ Wurzburg Wurzburg Germany D-97080 agnost, D-97080 Wurzburg, Germany Med Hsch Hannover, Abt Neuroradiol, Zentrum Radiol, Hannover, Germany Med Hsch Hannover Hannover Germany l, Zentrum Radiol, Hannover, Germany
Titolo Testata:
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
fascicolo: 1, volume: 173, anno: 2001,
pagine: 18 - 23
SICI:
1438-9029(200101)173:1<18:QMIOPO>2.0.ZU;2-T
Fonte:
ISI
Lingua:
GER
Soggetto:
CEREBRAL BLOOD-FLOW; TEMPORAL RESOLUTION; MRI; QUANTIFICATION; ARTERIAL; VOLUME;
Keywords:
brain perfusion; brain blood flow; MR echo planar; MR perfusion study; MR pulse sequence;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Kostler, H Univ Wurzburg, Inst Rontgendiagnost, Josef Schneider Str 2,Bau 24, D-97080Wurzburg, Germany Univ Wurzburg Josef Schneider Str 2,Bau 24 Wurzburg Germany D-97080
Citazione:
H. Kostler e H. Becker, "Quantitative multi-slice imaging of perfusion of the brain.", ROFO-F RONT, 173(1), 2001, pp. 18-23

Abstract

Aim: To develop an MR pulse sequence that allows the determination of the quantitative perfusion of the brain by imaging the passage of a contrast agent bolus with high temporal and spatial resolution. Methods: An EPI sequence, EPIDET (Echo Planar Imaging using Different Echo Times), was developed that allows the acquisition of different slices at different echo times. The passage of a contrast agent bolus was recorded in a slice through the large brain feeding arteries at a short echo time (TE1 = 17 ms), while brain parenchyma was imaged in up to nine additional slices at a long echo time (TE2 = 34 ms). Results: The different echo times allowed the determination ofthe arterial input function (signal decrease to 32%-59% of baseline intensity) and gave a sufficient signal reduction (14-22%) for reliable quantification of perfusion in brain parenchyma. Conclusions: The combination of different echo times of the DUAL-FLASH sequence and the multislice capability of EPI sequences in the EPIDET sequence enables the quantification of multi-slice perfusion examinations. Compared to the DUAL-FLASH sequence EPIDET improves spatial and temporal resolution.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 19:03:54