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Titolo:
A prospective 2-year study of 75 patients with adult-onset septic arthritis
Autore:
Gupta, MN; Sturrock, RD; Field, M;
Indirizzi:
Univ Glasgow, Royal Infirm, Dept Med, Ctr Rheumat Dis, Glasgow G31 2ER, Lanark, Scotland Univ Glasgow Glasgow Lanark Scotland G31 2ER ow G31 2ER, Lanark, Scotland
Titolo Testata:
RHEUMATOLOGY
fascicolo: 1, volume: 40, anno: 2001,
pagine: 24 - 30
SICI:
1462-0324(200101)40:1<24:AP2SO7>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
BACTERIAL ARTHRITIS; RHEUMATOID-ARTHRITIS; JOINT INFECTIONS; HEALTH DISTRICT; DISEASE;
Keywords:
septic arthritis; clinical characteristics; risk factors; treatment; outcome;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Field, M Univ Glasgow, Royal Infirm, Dept Med, Ctr Rheumat Dis, 10 Alexandra Parade, Glasgow G31 2ER, Lanark, Scotland Univ Glasgow 10 Alexandra Parade Glasgow Lanark Scotland G31 2ER
Citazione:
M.N. Gupta et al., "A prospective 2-year study of 75 patients with adult-onset septic arthritis", RHEUMATOLOG, 40(1), 2001, pp. 24-30

Abstract

Aims and Methods. To assess the clinical features of septic arthritis and characterize therapeutic strategies and outcome in a prospective study of 75 patients selected by positive synovial fluid culture. Results. Underlying joint disease was present in 46 patients, 25 of whom had rheumatoid arthritis and 15 osteoarthritis. Eleven patients were i.v. drug abusers. Fifty-six per cent of cases involved the knee, 15% involved twoor more joints, and staphylococci and streptococci were cultured in > 90%. Seventy-eight per cent of patients lived in areas of high social deprivation. Fever was present in 64% and the white cell count (WCC) was normal in 38%. The C-reactive protein was elevated in 98%. Leg ulcers were present in 11% of all patients but in 38% of patients who died (P < 0.006). Median duration of antibiotic therapy was 15 days i.v. with subsequent oral treatmentfor 21 days. Thirty-seven per cent of cases required surgical intervention. Mortality was 11%. A raised WCC at presentation (P < 0.02) and the development of abnormal renal function (P < 0.015) were predictors of poor prognosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/02/20 alle ore 08:11:12