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Titolo:
Heart motion-adapted MR velocity mapping of blood velocity distribution downstream of aortic valve prostheses: Initial experience
Autore:
Kozerke, S; Hasenkam, JM; Nygaard, H; Paulsen, PK; Pedersen, EM; Boesiger, P;
Indirizzi:
Univ Zurich, Inst Biomed Engn & Med Informat, CH-8092 Zurich, Switzerland Univ Zurich Zurich Switzerland CH-8092 rmat, CH-8092 Zurich, Switzerland Swiss Fed Inst Technol, CH-8092 Zurich, Switzerland Swiss Fed Inst Technol Zurich Switzerland CH-8092 92 Zurich, Switzerland Aarhus Univ Hosp, Dept Cardiothorac & Vasc Surg, DK-8000 Aarhus, Denmark Aarhus Univ Hosp Aarhus Denmark DK-8000 sc Surg, DK-8000 Aarhus, Denmark Aarhus Univ Hosp, Inst Expt Clin Res, MR Ctr, DK-8000 Aarhus, Denmark Aarhus Univ Hosp Aarhus Denmark DK-8000 MR Ctr, DK-8000 Aarhus, Denmark
Titolo Testata:
RADIOLOGY
fascicolo: 2, volume: 218, anno: 2001,
pagine: 548 - 555
SICI:
0033-8419(200102)218:2<548:HMMVMO>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
STRESS-DISTRIBUTION DOWNSTREAM; CONTRAST FLOW MEASUREMENTS; RESPIRATORY MOTION; PULSATILE FLOW; QUANTIFICATION; ANGIOGRAPHY; REDUCTION;
Keywords:
heart, flow dynamics; heart, MR; heart, valves; magnetic resonance (MR), cine study; magnetic resonance (MR), physics; phantoms;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Boesiger, P Univ Zurich, Inst Biomed Engn & Med Informat, Gloriastr 35, CH-8092 Zurich, Switzerland Univ Zurich Gloriastr 35 Zurich Switzerland CH-8092 itzerland
Citazione:
S. Kozerke et al., "Heart motion-adapted MR velocity mapping of blood velocity distribution downstream of aortic valve prostheses: Initial experience", RADIOLOGY, 218(2), 2001, pp. 548-555

Abstract

PURPOSE: To investigate blood flow velocities and shear rates at two distances downstream of an artificial aortic valve in patients. MATERIALS AND METHODS: Blood velocity was quantified downstream of the valve prosthesis (for replacement after aortic valve stenosis or combined stenosis and regurgitation) in 10 patients by using a magnetic resonance (MR) cine velocity mapping method in which the imaging section position is adapted according to the excursion of the valvular plane of the heart. Two acquisitions were performed to display the blood velocity distributions one-fourth valve diameter and one valve diameter downstream of the valve and to quantify blood volumes and shear rates. RESULTS: The velocity profiles measured during flow acceleration one-fourth valve diameter downstream were characterized by a distinct pattern of twolateral jets and one central jet of antegrade flow. High shear rates were found along the leaflet tips. The profiles obtained one valve diameter downstream were skewed, with varying velocity patterns among patients. Peak shear rates were found close to the vessel wall. With correction for through-plane motion of the valve, the mean apparent regurgitant fraction (+/- SD) was 14% +/- 6; the mean regurgitant fraction without correction was 9% +/- 5. CONCLUSION: The described noninvasive procedure for velocity mapping enables measurements close to the valve and thus evaluation of blood flow patterns with respect to valve design in humans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/07/20 alle ore 19:24:37