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Titolo:
Stroke and idiopathic Parkinson's disease: Does a shortage of dopamine offer protection against stroke?
Autore:
Korten, A; Lodder, J; Vreeling, F; Boreas, A; van Raak, L; Kessels, F;
Indirizzi:
Univ Hosp Maastricht, Dept Neurol, NL-6202 AZ Maastricht, Netherlands UnivHosp Maastricht Maastricht Netherlands NL-6202 AZ icht, Netherlands Univ Hosp Maastricht, Dept Clin Epidemiol & Med Technol Assessment, Maastricht, Netherlands Univ Hosp Maastricht Maastricht Netherlands nt, Maastricht, Netherlands
Titolo Testata:
MOVEMENT DISORDERS
fascicolo: 1, volume: 16, anno: 2001,
pagine: 119 - 123
SICI:
0885-3185(200101)16:1<119:SAIPDD>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
RISK-FACTORS; MORTALITY; INFARCTS; DEATH; HOMOCYSTEINE; POPULATION; LACUNAR;
Keywords:
idiopathic Parkinson's disease; stroke; cerebrovascular disease; dopamine deficiency;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Korten, A Univ Hosp Maastricht, Dept Neurol, POB 5800, NL-6202 AZ Maastricht, Netherlands Univ Hosp Maastricht POB 5800 Maastricht Netherlands NL-6202 AZ
Citazione:
A. Korten et al., "Stroke and idiopathic Parkinson's disease: Does a shortage of dopamine offer protection against stroke?", MOVEMENT D, 16(1), 2001, pp. 119-123

Abstract

Data on the relationship between idiopathic Parkinson's disease (IPD) and stroke are conflicting. In this study, we examined the frequency uf IPD in stroke patients registered in the Maastricht Stroke Registry. With the use of three different search strategies, we found eight individuals with IPD amongst a total of 1.516 stroke patients. We had expected to find approximately 30 IPD patients (relative risk 0.27; 95% confidence interval 0.11-0.53). based on IPD prevalence figures from a Dutch population-based study. We speculate that dopamine deficiency may protect against ischaemic brain damager perhaps by reducing the effects of excitotoxicity.

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Documento generato il 27/11/20 alle ore 13:49:46