Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
A model of the cerebral and cerebrospinal fluid circulations to examine asymmetry in cerebrovascular reactivity
Autore:
Piechnik, SK; Czosnyka, M; Harris, NG; Minhas, PS; Pickard, JD;
Indirizzi:
Addenbrookes Hosp, Acad Neurosurg Unit, Cambridge CB2 2QQ, England Addenbrookes Hosp Cambridge England CB2 2QQ , Cambridge CB2 2QQ, England Addenbrookes Hosp, MRC, Ctr Brain Repair, Wolfson Brain Imaging Ctr, Cambridge, England Addenbrookes Hosp Cambridge England ain Imaging Ctr, Cambridge, England
Titolo Testata:
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
fascicolo: 2, volume: 21, anno: 2001,
pagine: 182 - 192
SICI:
0271-678X(200102)21:2<182:AMOTCA>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPERIMENTAL INTRACRANIAL HYPERTENSION; INTRACEREBRAL STEAL PHENOMENON; PERFUSION-PRESSURE; BLOOD-FLOW; MATHEMATICAL-MODEL; VENOUS SYSTEM; HEAD-INJURY; AUTOREGULATION; HEMODYNAMICS; COMPRESSION;
Keywords:
cerebral blood flow; mathematical model; simulation; steal effect; collateral blood supply;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Piechnik, SK Addenbrookes Hosp, Acad Neurosurg Unit, Hills Rd,POB 167, Cambridge CB2 2QQ, England Addenbrookes Hosp Hills Rd,POB 167 Cambridge England CB2 2QQ
Citazione:
S.K. Piechnik et al., "A model of the cerebral and cerebrospinal fluid circulations to examine asymmetry in cerebrovascular reactivity", J CEREBR B, 21(2), 2001, pp. 182-192

Abstract

The authors examined the steal phenomenon using a new mathematical model of cerebral blood flow and the: cerebrospinal fluid circulation. In this model, the two hemispheres are connected through the circle of Willis by an anterior communicating artery (ACoA) of varying size. The right hemisphere has no cerebrovascular reactivity and the left is normally reactive. The authors studied the asymmetry of hemispheric blood flow in response to simulated changes in arterial blood pressure and carbon dioxide concentration. The hemispheric blood flow was dependent on the local regulatory capacity but not on the size of the ACoA. Flow through the ACoA and carotid artery was strongly dependent on the size of the communicating artery. A global interhemispheric "steal effect" was demonstrated to be unlikely to occur in subjects with non-stenosed carotid arteries. Vasoreactive effects on intracranial pressure had a major influence on the circulation in both hemispheres, provoking additional changes in blood flow on the nonregulating side. A method for the quantification of the crosscirculatory capacity has been proposed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 11:56:04