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Titolo:
Predictors for cutaneous basal- and squamous-cell carcinoma among actinically damaged adults
Autore:
Foote, JA; Harris, RB; Giuliano, AR; Roe, DJ; Moon, TE; Cartmel, B; Alberts, DS;
Indirizzi:
Univ Arizona, Arizona Canc Ctr, Tucson, AZ USA Univ Arizona Tucson AZ USA niv Arizona, Arizona Canc Ctr, Tucson, AZ USA Univ Arizona, Coll Publ Hlth, Tucson, AZ USA Univ Arizona Tucson AZ USAUniv Arizona, Coll Publ Hlth, Tucson, AZ USA
Titolo Testata:
INTERNATIONAL JOURNAL OF CANCER
fascicolo: 1, volume: 95, anno: 2001,
pagine: 7 - 11
SICI:
0020-7136(20010120)95:1<7:PFCBAS>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONMELANOMA SKIN-CANCER; SOLAR KERATOSES; RISK-FACTORS; INCIDENCE RATES; EPIDEMIOLOGY; PREVENTION; DISEASE; HEALTH;
Keywords:
non-melanoma skin cancer; basal-cell carcinoma; squamous-cell carcinoma; skin cancer; risk factors; epidemiology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Foote, JA Univ Hawaii, Canc Res Ctr, Lauhala St,Ste 505, Honolulu, HI 96813 USA Univ Hawaii Lauhala St,Ste 505 Honolulu HI USA 96813 I 96813 USA
Citazione:
J.A. Foote et al., "Predictors for cutaneous basal- and squamous-cell carcinoma among actinically damaged adults", INT J CANC, 95(1), 2001, pp. 7-11

Abstract

Risk factors for non-melanoma skin cancer among populations with evidence of precursor damage are not well described, We examined and compared risk factors associated with the development of cutaneous basal-cell (BCC) or squamous-cell (SCC) carcinoma among a group of 918 adults with significant sundamage (greater than or equal to 10 clinically assessable actinic keratoses) but no prior history of skin cancer, These adults were participants in aii-year skin chemoprevention trial between 1985 and 1992, who had been randomized to the placebo group and followed for occurrence of skin cancer, During the study, a total of 129 first SCC and 164 first BCC lesions were diagnosed. The overall BCC and SCC incidence rates for this group of men and women, mean age 61 years, were 4,106 and 3,198 per 100,000 person-years, respectively, Different constitutional and exposure factors were independentlyassociated with BCC compared to SCC, Only increased age independently predicted BCC occurrence among this population. In contrast, older age along with male gender, natural red hair color and adult residence in Arizona for 10 or more years independently predicted SCC occurrence. The substantial incidence of skin cancer found among this population confirms the need for active dermatological monitoring among individuals with multiple visible actinic lesions. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 09:34:34