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Titolo:
Improvement of image resolution and quantitative accuracy in clinical Single Photon Emission Computed Tomography
Autore:
Beekman, FJ; Kamphuis, C; King, MA; van Rijk, PP; Viergever, MA;
Indirizzi:
Univ Utrecht Hosp, Image Sci Inst, NL-3584 CX Utrecht, Netherlands Univ Utrecht Hosp Utrecht Netherlands NL-3584 CX CX Utrecht, Netherlands
Titolo Testata:
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
fascicolo: 2, volume: 25, anno: 2001,
pagine: 135 - 146
SICI:
0895-6111(200103/04)25:2<135:IOIRAQ>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
ITERATIVE RECONSTRUCTION ALGORITHMS; SCATTER CORRECTION; CONE-BEAM; ATTENUATION CORRECTION; MAXIMUM-LIKELIHOOD; SIMULTANEOUS TRANSMISSION; SPECT RECONSTRUCTION; COMPENSATION METHODS; PRACTICAL METHOD; ML-EM;
Keywords:
radionuclide imaging; SPECT; collimator; scatter; cardiac imaging; regularisation; reconstruction; cone-beam; attenuation correction; inverse problems;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
71
Recensione:
Indirizzi per estratti:
Indirizzo: Beekman, FJ Univ Utrecht Hosp, Image Sci Inst, E 02-222,Heidelberglaan 100, NL-3584 CXUtrecht, Netherlands Univ Utrecht Hosp E 02-222,Heidelberglaan 100 Utrecht Netherlands NL-3584 CX
Citazione:
F.J. Beekman et al., "Improvement of image resolution and quantitative accuracy in clinical Single Photon Emission Computed Tomography", COMP MED IM, 25(2), 2001, pp. 135-146

Abstract

Clinical Single Photon Emission Computed Tomography (SPECT) is a scanning technique which acquires gamma-camera images ('projections') over a range of angles around a patient. These projections allow the reconstruction of cross sectional ('tomographic') images of the gamma-radiating pharmaceutical distribution in the patient, thus providing interesting information about the functioning of organs and tissues. SPECT images are seriously affected by a variety of image degrading processes. Restrictions on the amount of radio-pharmaceutical that can be administered to a patient cause noise in the projections and the limited spatial resolution of the gamma-camera results in blurring of the projections. In addition to these image degradations, the reconstruction of cross-sections iscomplicated by Compton scattering of gamma -photons in tissue, which causes attenuation of the photon flux received by the gamma-camera and causes improper detection of photons which have been scattered in tissue. This results in some additional blurring and loss of accuracy of the SPECT images in predicting activity concentrations. Tremendous efforts have been made to improve the quantitative accuracy andthe spatial resolution of SPECT, and to reduce the noise in the reconstructed images. These efforts have resulted in corrective reconstruction algorithms, which are generally based on incorporation of accurate models of the main image degrading factors. Improvements of the data acquisition hardwarecan further increase image quality. In this paper, the image formation process of SPECT, including image-degrading factors, is explained. In addition, reconstruction algorithms and hardware modifications are reviewed, and their effects on image quality are illustrated with physical phantom and simulation experiments. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 05:10:49