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Titolo:
Usefulness of accelerated exercise following mild hyperventilation for theinduction of coronary artery spasm - Comparison with an acetylcholine test
Autore:
Sueda, S; Fukuda, H; Watanabe, K; Ochi, N; Kawada, H; Hayashi, Y; Uraoka, T;
Indirizzi:
Saiseikai Saijo Hosp, Dept Cardiol, Saijo, Ehime 7930027, Japan Saiseikai Saijo Hosp Saijo Ehime Japan 7930027 aijo, Ehime 7930027, Japan Kita Med Assoc Hosp, Dept Cardiol, Ozu, Japan Kita Med Assoc Hosp Ozu Japan Med Assoc Hosp, Dept Cardiol, Ozu, Japan
Titolo Testata:
CHEST
fascicolo: 1, volume: 119, anno: 2001,
pagine: 155 - 162
SICI:
0012-3692(200101)119:1<155:UOAEFM>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLD PRESSOR TEST; VARIANT ANGINA; SEGMENT ELEVATION; PROVOCATION TEST; ERGONOVINE; ARTERIOGRAPHY; FREQUENCY; ATTACKS;
Keywords:
accelerated exercise; acetylcholine; coronary spastic angina; hyperventilation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Sueda, S Saiseikai Saijo Hosp, Dept Cardiol, Tsuitachi 269-1, Saijo, Ehime7930027,Japan Saiseikai Saijo Hosp Tsuitachi 269-1 Saijo Ehime Japan 7930027 an
Citazione:
S. Sueda et al., "Usefulness of accelerated exercise following mild hyperventilation for theinduction of coronary artery spasm - Comparison with an acetylcholine test", CHEST, 119(1), 2001, pp. 155-162

Abstract

Study objectives: This study was performed to compare the results of accelerated exercise following mild hyperventilation and a standard acetylcholine (ACh) test for the induction of coronary artery spasm in patients with drug-induced coronary artery spasm. Methods and results: The subjects were 74 patients with angiographically confirmed coronary artery spasm who were examined using accelerated exercisetie, exercise that was accelerated every minute according to the protocol of Bruce and Horsten) following mild hyperventilation and who were not receiving any medication. ACh was injected in incremental doses of 20 mug and 50 mug into the right coronary artery and incremental doses of 20 mug, 50 mug, and 100 mug into the left coronary artery. Positive coronary spasm was defined as greater than or equal to 99% luminal narrowing. Accelerated exercise following a mild hyperventilation test was as useful for detecting evidence of ischemia as was an ACh test (48 patients [64.9%] vs 49 patients [66.2%], respectively; not significant). No difference was observed between ischemic changes on ECG as a result of the newly combined method and the occurrence of ACh-induced spasm. ACh-induced coronary vasospasm occurred in gl patients (82.4%). In the remaining 13 patients, intracoronary administration of ergonovine provoked coronary spasms. No serious irreversible complications were detected as a result of this newly combined method. Conclusions: The effectiveness of our newly combined procedure is equivalent to that of an ACh test to diagnose patients with coronary artery spasm.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 21:47:30