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Titolo:
Neuron addition and enlargement in juvenile and adult animals
Autore:
Farel, PB; McIlwain, DL;
Indirizzi:
Univ N Carolina, Dept Cell & Mol Physiol, Chapel Hill, NC 27599 USA Univ NCarolina Chapel Hill NC USA 27599 ysiol, Chapel Hill, NC 27599 USA Univ N Carolina, Neurobiol Curriculum, Chapel Hill, NC 27599 USA Univ N Carolina Chapel Hill NC USA 27599 culum, Chapel Hill, NC 27599 USA
Titolo Testata:
BRAIN RESEARCH BULLETIN
fascicolo: 5, volume: 53, anno: 2000,
pagine: 537 - 546
SICI:
0361-9230(20001115)53:5<537:NAAEIJ>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
NERVE GROWTH-FACTOR; LATERAL MOTOR COLUMN; RAT SCIATIC-NERVE; SENSORY NEURON; FACTOR-I; MOTONEURON NUMBER; TRANSGENIC MICE; XENOPUS-LAEVIS; DIFFERENTIAL EXPRESSION; POSTNATAL-DEVELOPMENT;
Keywords:
motoneuron; sensory neuron; neuron size; neuron number; growth hormone;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
91
Recensione:
Indirizzi per estratti:
Indirizzo: Farel, PB Univ N Carolina, Dept Cell & Mol Physiol, Campus Box 7545, Chapel Hill, NC27599 USA Univ N Carolina Campus Box 7545 Chapel Hill NC USA 27599 599 USA
Citazione:
P.B. Farel e D.L. McIlwain, "Neuron addition and enlargement in juvenile and adult animals", BRAIN RES B, 53(5), 2000, pp. 537-546

Abstract

Locomotion requires bilateral symmetry of neural circuitry in the spinal cord. Although not well understood, the mechanisms responsible for establishing and maintaining this symmetry must balance the numbers, sizes, and connectivity of the neurons on both sides of the spinal cord. Those mechanisms do not cease to function after embryogenesis, since there is substantial evidence that these properties continue to change as juvenile animals grow toadult size. We review the evidence that spinal neuron number and size increase in growing juvenile frogs and mammals. We postulate that these increases are regulated by both local and systemic factors. In addition, we discuss evidence that axotomy of spinal sensory and motor neurons also enlists local and systemic regulatory factors, some of which may also be operative innormal growth and development. (C) 2001 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 20:39:10