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Titolo:
Vestibular efferent neurons project to the flocculus
Autore:
Shinder, ME; Purcell, IM; Kaufman, GD; Perachio, AA;
Indirizzi:
Univ Texas, Med Branch, Dept Otolaryngol, Galveston, TX 77555 USA Univ Texas Galveston TX USA 77555 pt Otolaryngol, Galveston, TX 77555 USA
Titolo Testata:
BRAIN RESEARCH
fascicolo: 1-2, volume: 889, anno: 2001,
pagine: 288 - 294
SICI:
0006-8993(20010119)889:1-2<288:VENPTT>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERIPHERAL INNERVATION PATTERNS; SQUIRREL-MONKEY; OCULAR REFLEX; SEMICIRCULAR CANALS; HORSERADISH-PEROXIDASE; VESTIBULOOCULAR REFLEX; AFFERENT-PROJECTIONS; CEREBELLAR FLOCCULUS; RETROGRADE TRANSPORT; SECONDARY NEURONS;
Keywords:
gerbil; HRP; BDA; fluorogold; fluorescent beads; vestibular efferent neurons; motor control;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Perachio, AA Univ Texas, Med Branch, Dept Otolaryngol, 7-102 MRB, Galveston, TX 77555 USA Univ Texas 7-102 MRB Galveston TX USA 77555 ton, TX 77555 USA
Citazione:
M.E. Shinder et al., "Vestibular efferent neurons project to the flocculus", BRAIN RES, 889(1-2), 2001, pp. 288-294

Abstract

A bilateral projection from the vestibular efferent neurons, located dorsal to the genu of the facial nerve, to the cerebellar flocculus and ventral paraflocculus was demonstrated. Efferent neurons were double-labeled by theunilateral injections of separate retrograde tracers into the labyrinth and into the floccular and ventral parafloccular lobules. Efferent neurons were found with double retrograde tracer labeling both ipsilateral and contralateral to the sites of injection. No double labeling was found when using a fluorescent tracer with non-fluorescent tracers such as horseradish peroxidase (HRP) or biotinylated dextran amine (BDA), but large percentages of efferent neurons were found to be double labeled when using two fluorescent substances including: fluorogold, microruby dextran amine, or rhodamine labeled latex beads. These data suggest a potential role for vestibular efferent neurons in modulating the dynamics of the vestibule-ocular reflex (VOR) during normal and adaptive conditions. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 15:55:30