Catalogo Articoli (Spogli Riviste)
OPAC HELP
Titolo: Effects of Ninjin-to on levels of brain-gut peptides (motilin, vasoactive intestinal peptide, gastrin, and somatostatin) in human plasma
Autore: Naito, T; Itoh, H; Nagano, T; Takeyama, M;
- Indirizzi:
- Oita Med Univ, Dept Clin Pharm, Oita 8795593, Japan Oita Med Univ Oita Japan 8795593 v, Dept Clin Pharm, Oita 8795593, Japan
- Titolo Testata:
- BIOLOGICAL & PHARMACEUTICAL BULLETIN
fascicolo: 2,
volume: 24,
anno: 2001,
pagine: 194 - 196
- SICI:
- 0918-6158(200102)24:2<194:EONOLO>2.0.ZU;2-C
- Fonte:
- ISI
- Lingua:
- ENG
- Soggetto:
- MIGRATING MOTOR COMPLEX; ENZYME-IMMUNOASSAY; IMMUNOREACTIVE SUBSTANCE; INHIBITORY NEURONS; BOVINE-MILK; NEUROTRANSMITTER; POLYPEPTIDE; SCLERODERMA; OCTREOTIDE;
- Keywords:
- Ninjin-to; motilin; somatostatin; vasoactive intestinal peptide; gastrin; Kampo;
- Tipo documento:
- Article
- Natura:
- Periodico
- Settore Disciplinare:
- Life Sciences
- Citazioni:
- 31
- Recensione:
- Indirizzi per estratti:
- Indirizzo: Naito, T Oita Med Univ, Dept Clin Pharm, Hasama Machi, Oita 8795593, JapanOita Med Univ Hasama Machi Oita Japan 8795593 ita 8795593, Japan
-
-
-
- Citazione:
- T. Naito et al., "Effects of Ninjin-to on levels of brain-gut peptides (motilin, vasoactive intestinal peptide, gastrin, and somatostatin) in human plasma", BIOL PHAR B, 24(2), 2001, pp. 194-196
Abstract
We examined the effects of Ninjin-to, a traditional Chinese (Kampo) medicine, on the levels of brain-gut peptides (motilin, vasoactive intestinal peptide (VIP), gastrin, and somatostatin) in plasma from healthy subjects. A single oral administration of Ninjin-to, at a dose of 6.0 g, caused significant increases in plasma motilin levels at 40 to 90 min and somatostatin levels at 20 to 90 min, compared with a placebo treated group. Transient elevations of gastrin levels in the placebo group were inhibited by administration of Ninjin-to, but the medicine did not alter the levels of VIP. In conclusion, these results suggest that pharmacological effects of Ninjin-to on gastrointestinal functions closely relate to changes of motilin, gastrin, and somatostatin-immunoreactive substance levels in human plasma.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 02:10:59