Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
HYPOXIC VENTILATORY RESPONSE AND BREATHLESSNESS FOLLOWING HYPOCAPNIC AND ISOCAPNIC HYPERVENTILATION
Autore:
CHIN KZ; OHI M; KITA H; OTSUKA N; OKU Y; MISHIMA M; KUNO KS;
Indirizzi:
KYOTO UNIV,CHEST DIS RES INST,DEPT CLIN PHYSIOL,SAKYO KU,SHOGOIN KAWAHARACHO 53 KYOTO 606 JAPAN
Titolo Testata:
Chest
fascicolo: 1, volume: 112, anno: 1997,
pagine: 154 - 163
SICI:
0012-3692(1997)112:1<154:HVRABF>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
SHORT-TERM POTENTIATION; VOLUNTARY HYPERVENTILATION; CONSCIOUS HUMANS; MECHANISMS; EXERCISE; DYSPNEA; AFTERDISCHARGE; DRIVE; SLEEP;
Keywords:
HYPOXIC VENTILATORY; RESPONSE; POSTHYPERVENTILATION HYPERPNEA; POSTHYPERVENTILATION HYPOXEMIA; VAS SCORE; VOLUNTARY HYPERVENTILATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
K.Z. Chin et al., "HYPOXIC VENTILATORY RESPONSE AND BREATHLESSNESS FOLLOWING HYPOCAPNIC AND ISOCAPNIC HYPERVENTILATION", Chest, 112(1), 1997, pp. 154-163

Abstract

Study objectives: To investigate the etiology of posthyperventilation(post-HV) hypoxemia following voluntary hyperventilation (VHV), we examined the effects of hypocapnic (hypo-CO2) and isocapnic (iso-CO2) VHV on the hypoxic ventilatory response (O-2-response) and on the sensation of breathlessness during O-2-response. Methods: O-2-responses and visual analog scale (VAS) scores for estimating breathlessness in 10 normal subjects during the O-2-response under iso-CO2 conditions and under hypo-CO2 conditions immediately following voluntary maximal HV of 3 min duration were examined. Results: Although there was no significant difference in the post-HV ventilation levels following hypo-CO2 vs iso-CO2 VHV, the VAS scores at the start of the O-2-response followinghypo-CO2 VHV (30.2+/-24.2 mm) were significantly higher (p<0.05) thanthe VAS scores at the start of the O-2-response following iso-CO2 VHV(13.7+/-8.4 mm). However, VHV did not have a significant effect on the O-2-response at 2 min after the VHV when the arterial O-2 saturationSaO(2)) was below 90%. The nonsteady-state hypo-CO2 induced by VHV greatly attenuated the O-2-response below 90% SaO(2) and VAS scores at 70% SaO(2). Conclusions: Elevated VAS scores immediately following the hypo-CO2 VHV, which might be independent of actual breathing levels, and the attenuation of the O-2-response following the hypo-CO2 VHV werenot due to input from lung and chest wall mechanoreceptors induced bythe hyperpnea itself, but rather to the hypo-CO2 induced by hyperpnea.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 06:16:59