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Titolo:
A current assessment of rurally linked exposures as potential risk factorsfor sarcoidosis
Autore:
Kajdasz, DK; Lackland, DT; Mohr, LC; Judson, MA;
Indirizzi:
Med Univ S Carolina, Dept Biometry & Epidemiol, Charleston, SC 29425 USA Med Univ S Carolina Charleston SC USA 29425 iol, Charleston, SC 29425 USA Med Univ S Carolina, Dept Pulm & Crit Care Med, Charleston, SC 29425 USA Med Univ S Carolina Charleston SC USA 29425 Med, Charleston, SC 29425 USA Med Univ S Carolina, Environm Biosci Assessment Program, Charleston, SC 29425 USA Med Univ S Carolina Charleston SC USA 29425 ram, Charleston, SC 29425 USA
Titolo Testata:
ANNALS OF EPIDEMIOLOGY
fascicolo: 2, volume: 11, anno: 2001,
pagine: 111 - 117
SICI:
1047-2797(200102)11:2<111:ACAORL>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
LUNG ALVEOLAR INJURY; WOOD SMOKE; CONTROL SELECTION; CHILDHOOD-CANCER; INHALATION; FIREFIGHTERS; EMISSIONS; CHILDREN; DISEASE; STOVES;
Keywords:
case-control studies; environmental exposure; epidemiology; sarcoidosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Lackland, DT Med Univ S Carolina, Dept Biometry & Epidemiol, Rutledge Tower 1125, Charleston, SC 29425 USA Med Univ S Carolina Rutledge Tower 1125 Charleston SC USA 29425
Citazione:
D.K. Kajdasz et al., "A current assessment of rurally linked exposures as potential risk factorsfor sarcoidosis", ANN EPIDEMI, 11(2), 2001, pp. 111-117

Abstract

PURPOSE: To identify and quantify the risk of developing sarcoidosis associated with specific rural exposures previously recognized as potential riskfactors for this disease. METHODS: A matched case-control design was carried out with a 2-to-1 ratioof controls to cases. Case exposure histories were determine from a detailed questionnaire collecting self-reported information covering the period from birth through disease development and comparing that to, exposure histories for the corresponding period in age-, race, and gender-matched controls identified using Random Digit Dial survey methodology. Conditional logistic regression was used to analyze the matched data while controlling for several baseline variables. RESULTS: A number of exposures were found to be univariately associated with the development of sarcoidosis including: the use of wood stoves, the use of fireplaces, the use of nonpublic water supplier, and living or workingon a farm. A dose-response gradient was detected from exposure to wood stoves and fireplaces continued to be significantly associated with sarcoidosis in multivariable models. CONCLUSIONS: The results of this study provide further support for the hypothesis that behaviors associated with rural living play some role in the development of sarcoidosis. This study further suggests that exposures involving the handling or burning of wood such as using wood stoves or fireplaces fur home heating may, in part, explain this rural association. Ann Epidemiol 2001;11:111-117. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 01:20:04