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Titolo:
Synthesis of macrocyclic bifunctional chelating agents: 1,4,7-tris(carboxymethyl)-10-(2-aminoethyl)-1,4,7,10-tetraazacyclododecane and 1,4,8-tris(carboxymethyl)-11-(2-aminoethyl)-1,4,8,11-tetraazacyclotetradecane
Autore:
Mishra, AK; Chatal, JF;
Indirizzi:
Inst Nucl Med & Allied Sci, Dept Radiopharmaceut, Delhi 110054, India InstNucl Med & Allied Sci Delhi India 110054 aceut, Delhi 110054, India Inst Biol, Lab Interact Recepteurs Ligands Immunocancerol &, INSERM, U463,F-44035 Nantes, France Inst Biol Nantes France F-44035 l &, INSERM, U463,F-44035 Nantes, France
Titolo Testata:
NEW JOURNAL OF CHEMISTRY
fascicolo: 2, volume: 25, anno: 2001,
pagine: 336 - 339
SICI:
1144-0546(2001)25:2<336:SOMBCA>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
MONOCLONAL-ANTIBODIES; CONTRAST AGENTS; METAL-IONS; BINDING; MACROMOLECULES; COMPLEXES; MONO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Mishra, AK Inst Nucl Med & Allied Sci, Dept Radiopharmaceut, Brig SK Mazumdar Marg, Delhi 110054, India Inst Nucl Med & Allied Sci Brig SK Mazumdar Marg Delhi India 110054
Citazione:
A.K. Mishra e J.F. Chatal, "Synthesis of macrocyclic bifunctional chelating agents: 1,4,7-tris(carboxymethyl)-10-(2-aminoethyl)-1,4,7,10-tetraazacyclododecane and 1,4,8-tris(carboxymethyl)-11-(2-aminoethyl)-1,4,8,11-tetraazacyclotetradecane", NEW J CHEM, 25(2), 2001, pp. 336-339

Abstract

The convenient, synthetically useful bifunctional chelating agents, 1,4,7-tris(carboxymethyl)-10-(2-aminoethyl)-1,4,7,10-tetraazacyclododecane and 1,4,8-tris(carboxymethyl)-11-(2-aminoethyl)-1,4,8,11-tetraazacyclotetradecane, were obtained by reaction of ethyl bromoacetate with 1,4,7,10-tetraazacyclododecane and 1,4,8,11-tetraaza-cyclotetradecane, followed by reaction with N-(2-bromoethyl)phthalimide. This method is proven to be more efficient to prepare bifunctional chelating agents with aliphatic side arms in high yields, above 53%.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 21:20:41