Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Gliomagenesis: Genetic alterations and mouse models
Autore:
Holland, EC;
Indirizzi:
Mem Sloan Kettering Canc Ctr, Dept Neurosurg, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr New York NY USA 10021 New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, Dept Neurol, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr New York NY USA 10021 New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, Dept Cell Biol, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr New York NY USA 10021 New York, NY 10021 USA
Titolo Testata:
NATURE REVIEWS GENETICS
fascicolo: 2, volume: 2, anno: 2001,
pagine: 120 - 129
SICI:
1471-0056(200102)2:2<120:GGAAMM>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
FIBROBLAST GROWTH-FACTOR; TUMOR-SUPPRESSOR GENE; HUMAN GLIOMAS; GLIOBLASTOMA-MULTIFORME; FACTOR RECEPTOR; BRAIN-TUMORS; CELL-LINES; IN-VITRO; EXPRESSION; MICE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
73
Recensione:
Indirizzi per estratti:
Indirizzo: Holland, EC Mem Sloan Kettering Canc Ctr, Dept Neurosurg, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr 1275 York Ave New York NY USA 10021
Citazione:
E.C. Holland, "Gliomagenesis: Genetic alterations and mouse models", NAT REV GEN, 2(2), 2001, pp. 120-129

Abstract

Glioblastoma muliforme is the most malignant of the primary brain tumours and is almost always fatal. The treatment strategies for this disease have not changed appreciably for many years and most are based on a limited understanding of the biology of the disease. However in the past decade, characteristic genetic alterations have been identified in gliomas that might underlie the initiation or progression of the disease. Recent modelling experiments in mice are helping to delineate the molecular aetiology of this disease and are providing systems to identify and test novel and rational therapeutic strategies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 10:48:02