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Titolo:
Perfusion-based segmentation of the human brain using similarity mapping
Autore:
Wiart, M; Rognin, N; Berthezene, Y; Nigoghossian, N; Froment, JC; Baskurt, A;
Indirizzi:
INSERM, CNRS, Res Unit, CREATIS, Lyon, France INSERM Lyon FranceINSERM, CNRS, Res Unit, CREATIS, Lyon, France Univ Lyon 1, LIGIM, F-69365 Lyon, France Univ Lyon 1 Lyon France F-69365Univ Lyon 1, LIGIM, F-69365 Lyon, France
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 2, volume: 45, anno: 2001,
pagine: 261 - 268
SICI:
0740-3194(200102)45:2<261:PSOTHB>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; CEREBROVASCULAR RESERVE CAPACITY; HIGH-RESOLUTION MEASUREMENT; TRACER BOLUS PASSAGES; CONTRAST AGENTS; VOLUME; MRI; ARTERY; NMR;
Keywords:
magnetic resonance imaging; cerebral perfusion; segmentation; contrast agent; relative cerebral blood volume;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Berthezene, Y Hop Croix Rousse, Serv Radiol, 93 Grande Rue de la Croix Rousse, F-69004 Lyon, France Hop Croix Rousse 93 Grande Rue de la Croix RousseLyon France F-69004
Citazione:
M. Wiart et al., "Perfusion-based segmentation of the human brain using similarity mapping", MAGN RES M, 45(2), 2001, pp. 261-268

Abstract

In this work, a method for segmenting human brain MR scans on the basis ofperfusion is described. This technique uses a measure of similarity between the time-intensity curves obtained with dynamic susceptibility contrast-enhanced MRI and a modeled curve of reference to isolate a tissue of interest, such as white or gray matter. The aim of this study was to validate the method by performing segmentation of white and gray matter in six controls. The relative regional blood volume gray-to-white matter ratio was used as a criterion to assess the quality of segmentation, On average, this ratio was 2.1 +/- 0.2, which is in good agreement with the literature, thus suggesting reliable segmentation. In the case of abnormal perfusion, time-intensity curves are different in shape than that of normal tissue. Therefore, this approach might allow the segmentation of pathological regions, and combined with an indicator-dilution analysis might offer new possibilities for characterizing a brain pathology. Magn Reson Med 45:261-268, 2001, (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:14:58