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Titolo:
Correlation of activation sizes between lateral geniculate nucleus and primary visual cortex in humans
Autore:
Chen, W; Zhu, XH;
Indirizzi:
Univ Minnesota, Sch Med, Dept Radiol, Ctr Magnet Resonance Res, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 ce Res, Minneapolis, MN 55455 USA
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 2, volume: 45, anno: 2001,
pagine: 202 - 205
SICI:
0740-3194(200102)45:2<202:COASBL>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN BRAIN; SENSORY STIMULATION; FUNCTIONAL MRI; LAMINAR; IMAGES; MONKEY; FIELDS; FMRI; BOLD; RAT;
Keywords:
human brain; visual system; lateral geniculate nucleus; primary visual cortex; functional MRI; high-resolution fMRI; high magnetic field; neural activity; activation correlation; neural network;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Chen, W Univ Minnesota, Sch Med, Dept Radiol, Ctr Magnet Resonance Res, 2021 6th St SE, Minneapolis, MN 55455 USA Univ Minnesota 2021 6th St SE Minneapolis MN USA 55455 N 55455 USA
Citazione:
W. Chen e X.H. Zhu, "Correlation of activation sizes between lateral geniculate nucleus and primary visual cortex in humans", MAGN RES M, 45(2), 2001, pp. 202-205

Abstract

It is well established that the lateral geniculate nucleus (LGN) and the primary visual cortex (V1) are retinotopically organized. This similarity isexpected to reflect a correlation of activation sizes between V1 and LGN during visual stimulation. However, it is a challenge to determine this functional correlation experimentally in the human brain using most neuroimaging techniques due to their low sensitivity for detecting small LGN activation in the thalamus. The purpose of this study was to examine the functional correlation of activation sizes between LGN and V1 during fullfield and hemifield visual stimulation using a large visual field and high-resolution fMRI technique at 4 Tesla. The correlation was determined by comparing the V1and LGN activation size ratios between the left and right hemispheres of the same subjects. The results reveal 1) a linear correlation of functional activation size ratio between LGN and V1 with a correlation coefficient of 0.96, and 2) the capability of fMRI for quantifying spatial correlation between cortical and subcortical activation. Magn Reson Med 45:202-205, 2001, (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 19:01:54