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Titolo:
Cervical lymph node metastases of head and neck cancer.
Autore:
Remmert, S; Rottmann, M; Reichenbach, M; Sommer, K; Friedrich, HJ;
Indirizzi:
UKL, Klin Hals Nasen Ohrenheilkunde, D-23538 Lubeck, Germany UKL Lubeck Germany D-23538 Nasen Ohrenheilkunde, D-23538 Lubeck, Germany
Titolo Testata:
LARYNGO-RHINO-OTOLOGIE
fascicolo: 1, volume: 80, anno: 2001,
pagine: 27 - 35
SICI:
1615-0007(200101)80:1<27:CLNMOH>2.0.ZU;2-D
Fonte:
ISI
Lingua:
GER
Soggetto:
SQUAMOUS-CELL-CARCINOMA; LARYNGEAL CARCINOMA; DISSECTION; PATTERNS; SURGERY; MANAGEMENT; TRACT;
Keywords:
lymph node metastases; head and neck cancer; neck dissection; survival rate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Remmert, S UKL, Klin Hals Nasen Ohrenheilkunde, Ratzeburger Allee 160, D-23538 Lubeck, Germany UKL Ratzeburger Allee 160 Lubeck Germany D-23538 beck, Germany
Citazione:
S. Remmert et al., "Cervical lymph node metastases of head and neck cancer.", LARY RH OTO, 80(1), 2001, pp. 27-35

Abstract

One of the most important criteria of malignancy of head and neck cancer are the cervical lymph metastases. Being significant for the therapeutical plan is how tumor depending parameters like T-stage, degree of differentiation and tumor localisation will influence the N-stage and therefore the extension of neck dissection. Method: To evaluate the pattern of formations of metastases and the success of therapy a retrospective study was performed on 405 patients with carcinoma of the oral cavity (n=47), the oropharynx (n=117), the hypopharynx (n=47) and the larynx (n=193). Results: By the time of surgery carcinoma of the hypopharynx were most frequently accompanied by cervical metastases (80 %), followed by carcinoma of the oropharynx (70%), the oral cavity (52 %) and the larynx (26%). Occurrence and extension of regional lymph node metastases correlated well with T-stages and degree of differentiation. After surgical therapy locoregional recurrence could be observed in 5.2% of the patients. Five-year-survival rate was reduced to 50% onpatients with positive lymph nodes. The different tumour sites showed preferred patterns of metastatic spread, without complete avoidance of certain levels. Conclusion: For the decision on indication and extent of neck dissection the preoperative diagnostic (ultrasound, CT-scan, MRI), localisation of tumour, T-stage, degree of differentiation and the knowledge of typical metastatic spread must be considered.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 15:38:13