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Titolo:
Clinical relevance of the primary findings of the MTA: Success rates basedon severity of ADHD and ODD symptoms at the end of treatment
Autore:
Swanson, JM; Kraemer, HC; Hinshaw, SP; Arnold, LE; Conners, CK; Abikoff, HB; Clevenger, W; Davies, M; Elliott, GR; Greenhill, LL; Hechtman, L; Hoza, B; Jensen, PS; March, JS; Newcorn, JH; Owens, EB; Pelham, WE; Schiller, E; Severe, JB; Simpson, S; Vitiello, B; Wells, K; Wigal, T; Wu, M;
Indirizzi:
Univ Calif Irvine, Child Dev Ctr, Irvine, CA 92612 USA Univ Calif Irvine Irvine CA USA 92612 Child Dev Ctr, Irvine, CA 92612 USA New York State Psychiat Inst, New York, NY 10032 USA New York State Psychiat Inst New York NY USA 10032 New York, NY 10032 USA Columbia Univ, Sch Publ Hlth, Div Biostat, New York, NY 10032 USA ColumbiaUniv New York NY USA 10032 , Div Biostat, New York, NY 10032 USA Univ Calif Berkeley, Berkeley, CA 94720 USA Univ Calif Berkeley Berkeley CA USA 94720 erkeley, Berkeley, CA 94720 USA Duke Univ, Durham, NC 27706 USA Duke Univ Durham NC USA 27706Duke Univ, Durham, NC 27706 USA Univ Calif Los Angeles, Los Angeles, CA USA Univ Calif Los Angeles Los Angeles CA USA s Angeles, Los Angeles, CA USA Long Isl Jewish Med Ctr, New Hyde Park, NY USA Long Isl Jewish Med Ctr New Hyde Park NY USA Ctr, New Hyde Park, NY USA Montreal Childrens Hosp, Montreal, PQ H3H 1P3, Canada Montreal Childrens Hosp Montreal PQ Canada H3H 1P3 al, PQ H3H 1P3, Canada CUNY, Mt Sinai Med Ctr, New York, NY USA CUNY New York NY USACUNY, Mt Sinai Med Ctr, New York, NY USA Univ Pittsburgh, Pittsburgh, PA 15260 USA Univ Pittsburgh Pittsburgh PA USA 15260 tsburgh, Pittsburgh, PA 15260 USA Stanford Univ, Stanford, CA 94305 USA Stanford Univ Stanford CA USA 94305Stanford Univ, Stanford, CA 94305 USA
Titolo Testata:
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
fascicolo: 2, volume: 40, anno: 2001,
pagine: 168 - 179
SICI:
0890-8567(200102)40:2<168:CROTPF>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
ATTENTION-DEFICIT/HYPERACTIVITY DISORDER;
Keywords:
SNAP-IV ratings; orthogonal comparisons; logistic regression; multimodal superiority; clinical relevance;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Swanson, JM Univ Calif Irvine, Child Dev Ctr, 19722 MacArthur Blvd, Irvine, CA 92612 USA Univ Calif Irvine 19722 MacArthur Blvd Irvine CA USA 92612 USA
Citazione:
J.M. Swanson et al., "Clinical relevance of the primary findings of the MTA: Success rates basedon severity of ADHD and ODD symptoms at the end of treatment", J AM A CHIL, 40(2), 2001, pp. 168-179

Abstract

Objectives: To develop a categorical outcome measure related to clinical decisions and to perform secondary analyses to supplement the primary analyses of the NIMH Collaborative Multisite Multimodal Treatment Study of Children With Attention-Deficit/Hyperactivity Disorder (MTA). Method: End-of-treatment status was summarized by averaging the parent and teacher ratings of attention-deficit/hyperactivity disorder and oppositional defiant disorder symptoms on the Swanson, Nolan, and Pelham, version IV(SNAP-IV) scale, and low symptom-Severity ("Just a Little") on this continuous measure was set as a clinical cutoff to form a categorical outcome measure reflecting successful treatment. Three orthogonal comparisons of the treatment groups (combined treatment [Comb], medication management [MedMgt], behavioral treatment [Beh], and community comparison [CGI) evaluated hypotheses about the MTA medication algorithm ("Comb + MedMgt Versus Beh + CC"), multimodality superiority ("Comb versus MedMgt"), and psychosocial substitution ("Beh versus CC"). Results: The summary of SNAP-IV ratings across sources and domains increased the precision of measurement by 30%. The secondary analyses of group differences in success rates (Comb = 68%; MedMgt = 56%; Beh = 34%; CC = 25%)confirmed the targe effect of the MTA medication algorithm and a smaller effect of multimodality superiority, which was now statistically significant(p <.05). The psychosocial substitution effect remained negligible, and nonsignificant. Conclusion: These secondary analyses confirm the primary findings and clarify clinical decisions about the choice between multimodal andunimodal treatment with medication.

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Documento generato il 14/07/20 alle ore 12:22:10