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Titolo:
A bereavement support group intervention affects plasma burden of human immunodeficiency virus type 1 - Report of a randomized controlled trial
Autore:
Goodkin, K; Baldewicz, TT; Asthana, D; Khamis, I; Blaney, NT; Kumar, M; Burkhalter, JE; Leeds, B; Shapshak, P;
Indirizzi:
Univ Miami, Sch Med, Dept Psychiat & Behav Sci, Miami, FL 33136 USA Univ Miami Miami FL USA 33136 t Psychiat & Behav Sci, Miami, FL 33136 USA Univ Miami, Sch Med, Dept Neurol, Miami, FL USA Univ Miami Miami FL USAUniv Miami, Sch Med, Dept Neurol, Miami, FL USA Univ Miami, Dept Psychol, Coral Gables, FL 33124 USA Univ Miami Coral Gables FL USA 33124 Psychol, Coral Gables, FL 33124 USA PharmaRes Corp, Dept Virol, Morrisville, NC USA PharmaRes Corp Morrisville NC USA Corp, Dept Virol, Morrisville, NC USA Mem Sloan Kettering Canc Ctr, Dept Psychiat & Behav Sci, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr New York NY USA 10021 New York, NY 10021 USA Univ Miami, Sch Med, Dept Pathol, Miami, FL USA Univ Miami Miami FL USAUniv Miami, Sch Med, Dept Pathol, Miami, FL USA
Titolo Testata:
JOURNAL OF HUMAN VIROLOGY
fascicolo: 1, volume: 4, anno: 2001,
pagine: 44 - 54
SICI:
1090-9508(200101/02)4:1<44:ABSGIA>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIV-1 INFECTION; IMMUNE FUNCTION; HOMOSEXUAL MEN; VIRAL LOAD; ANTIRETROVIRAL THERAPY; DEPRESSIVE SYMPTOMS; COPING STYLE; IN-VITRO; GAY MEN; T-CELLS;
Keywords:
HIV; AIDS; behavior; viral load; bereavement; stress; support; therapy; HAART;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Goodkin, K Univ Miami, Sch Med, Dept Psychiat & Behav Sci, 1400 NW 10th Ave,803-A, Miami, FL 33136 USA Univ Miami 1400 NW 10th Ave,803-A Miami FL USA33136 33136 USA
Citazione:
K. Goodkin et al., "A bereavement support group intervention affects plasma burden of human immunodeficiency virus type 1 - Report of a randomized controlled trial", J HUMAN VIR, 4(1), 2001, pp. 44-54

Abstract

Objectives: This study investigates the potential impact of a bereavement support group on plasma viral load. Methods: A randomly selected subsample of human immunodeficiency virus type 1 (HIV-1)-positive homosexual men participating in a controlled clinical trial of a bereavement support group intervention was studied. The intervention consisted of one 90-minute group session per week for 10 weeks. The plasma HIV-1 RNA copy number was measured at baseline and after intervention (10 weeks) by the Roche AMPLICOR assay. Results: There was a significant effect of the intervention on the change on the plasma HIV-1 RNA copy number (limited control model, beta = -0.49, p= 0.02: extended control model, beta = -0.37, p = 0.01), independent of antiretroviral therapies; prophylactic therapies against potentially lethal HIV-1 associated conditions: CD4 cell count: viral load; and Centers for Disease Control and Prevention clinical disease stage at baseline. Conclusions: Bereavement support group interventions may prove to be not only a primary therapy for psychologic distress after bereavement but also an adjunctive therapy for sustained control of plasma viral load in conjunction with highly active antiretroviral therapy in this population.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:21:29