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Titolo:
Varicocele treatment in the light of evidence-based andrology
Autore:
Kamischke, A; Nieschlag, E;
Indirizzi:
Univ Munster, Inst Reprod Med, D-48129 Munster, Germany Univ Munster Munster Germany D-48129 eprod Med, D-48129 Munster, Germany
Titolo Testata:
HUMAN REPRODUCTION UPDATE
fascicolo: 1, volume: 7, anno: 2001,
pagine: 65 - 69
SICI:
1355-4786(200101/02)7:1<65:VTITLO>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
RANDOMIZED CONTROLLED TRIALS; MALE-INFERTILITY; VENA-SPERMATICA; SUBCLINICAL VARICOCELE; MEN; PREGNANCY; LIGATION; EMBOLIZATION; AZOOSPERMIA; PARAMETERS;
Keywords:
controlled clinical trials; counselling; evidence-based infertility; male infertility; varicocele;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Nieschlag, E Univ Munster, Inst Reprod Med, Domagkstr 11, D-48129 Munster,Germany Univ Munster Domagkstr 11 Munster Germany D-48129 r, Germany
Citazione:
A. Kamischke e E. Nieschlag, "Varicocele treatment in the light of evidence-based andrology", HUM REP UPD, 7(1), 2001, pp. 65-69

Abstract

Treatment of varicoceles became the most common treatment for male infertility merely on an empirical basis. However, in the age of evidence-based medicine it is surprising that only a few, and mainly recent, randomized controlled clinical trials with relevant outcome parameters have been publishedto allow adequate judgement of treatment effectiveness. Moreover, difficulties in study design could also be detected in most of these high-quality studies. Despite these difficulties and in contrast to the majority of uncontrolled studies on varicocelectomy, metaanalysis of these randomized controlled clinical studies involving 385 patients showed no significant treatment benefit and questions the common practice of varicocelectomy. Even the high-quality studies show conflicting results and therefore the topic of varicocele treatment will remain controversial and further randomized clinical trials should readdress this issue. For the time being, intervention by surgical or angiographic occlusion of the spermatic vein cannot be recommended.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/05/20 alle ore 09:52:48