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Titolo:
Diagnosis of "ASCUS" in women over age 50 is less likely to be associated with dysplasia
Autore:
Flynn, K; Rimm, DL;
Indirizzi:
Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06520 USA Yale Univ New Haven CT USA 06520 ed, Dept Pathol, New Haven, CT 06520 USA
Titolo Testata:
DIAGNOSTIC CYTOPATHOLOGY
fascicolo: 2, volume: 24, anno: 2001,
pagine: 132 - 136
SICI:
8755-1039(200102)24:2<132:DO"IWO>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ATYPICAL SQUAMOUS CELLS; UNDETERMINED SIGNIFICANCE; FOLLOW-UP; INTRAEPITHELIAL LESIONS; PAPANICOLAOU SMEARS; MANAGEMENT; POPULATION; CYTOLOGY; HISTORY; RISK;
Keywords:
atypical squamous cells of undetermined significance; postmenopausal; outcome; dysplasia; atrophy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Rimm, DL Yale Univ, Sch Med, Dept Pathol, BML-B122,310 Cedar St,POB 208023, New Haven, CT 06520 USA Yale Univ BML-B122,310 Cedar St,POB 208023 New Haven CT USA 06520
Citazione:
K. Flynn e D.L. Rimm, "Diagnosis of "ASCUS" in women over age 50 is less likely to be associated with dysplasia", DIAGN CYTOP, 24(2), 2001, pp. 132-136

Abstract

Many investigators have found that cervical dysplasia is common when follow-up data are obtained from patients with a diagnosis of atypical squamous cells of undetermined significance (ASCUS). This study tests the hypothesisthat ASCUS in older women is less likely to predict dysplasia than in younger women, and quantifies the difference. We constructed a retrospective case/control cohort from patients diagnosed with ASCUS by our service in 1997. Follow-up information was obtained on 150 patients over age 50 and a temporally matched control cohort under age 50. In women under 50, our control group, we found that 29.5% of patients had dysplasia on follow-up. This number is similar to that seen in many studies in the literature. In comparison, women over 50 showed only 12.8% of patients with any level of dysplasia. This difference is statistically significant by chi-square analysis, at P = 0.0077. A diagnosis of ASCUS in women over 50 yrs old is 2.3-fold less likely to be associated with dysplasia than that diagnosis in younger patients. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 10:03:02