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Titolo:
Cytoskeletal changes in cell transformation and tumorigenesis
Autore:
Pawlak, G; Helfman, DM;
Indirizzi:
Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA Cold Spring Harbor Lab Cold Spring Harbor NY USA 11724 rbor, NY 11724 USA
Titolo Testata:
CURRENT OPINION IN GENETICS & DEVELOPMENT
fascicolo: 1, volume: 11, anno: 2001,
pagine: 41 - 47
SICI:
0959-437X(200102)11:1<41:CCICTA>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOCAL ADHESION KINASE; TYPE-2 GENE-PRODUCT; SIGNAL-TRANSDUCTION; SMOOTH-MUSCLE; NONMUSCLE TROPOMYOSIN; EXTRACELLULAR-MATRIX; TYROSINE KINASE; RHO-GTPASES; 3T3 CELLS; EXPRESSION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
83
Recensione:
Indirizzi per estratti:
Indirizzo: Pawlak, G Cold Spring Harbor Lab, POB 100, Cold Spring Harbor, NY 11724 USA Cold Spring Harbor Lab POB 100 Cold Spring Harbor NY USA 11724 A
Citazione:
G. Pawlak e D.M. Helfman, "Cytoskeletal changes in cell transformation and tumorigenesis", CUR OP GEN, 11(1), 2001, pp. 41-47

Abstract

Research during the past couple of years has provided important new information as to how the actin cytoskeleton contributes to growth control in both normal and transformed cells. The cytoskeleton can no longer be viewed assimply a structural framework playing a role in cell shape and motile events such as cell movement, intracellular transport, contractile-ring formation and chromosome movement. More recent experiments show that the cytoskeleton plays a critical role in the regulation of various cellular processes linked to transformation including proliferation, contact inhibition, anchorage-independent cell growth, and apoptosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 06:24:45