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Titolo:
Growth regulation by oncogenes - new insights from model organisms
Autore:
Prober, DA; Edgar, BA;
Indirizzi:
Fred Hutchinson Canc Res Ctr, Mol & Cellular Biol Program, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr Seattle WA USA 98109 , Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr, Div Basic Sci, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr Seattle WA USA 98109 , Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr, Program Dev Biol, Seattle, WA 98109 USA FredHutchinson Canc Res Ctr Seattle WA USA 98109 , Seattle, WA 98109 USA Univ Washington, Seattle, WA 98105 USA Univ Washington Seattle WA USA 98105 iv Washington, Seattle, WA 98105 USA
Titolo Testata:
CURRENT OPINION IN GENETICS & DEVELOPMENT
fascicolo: 1, volume: 11, anno: 2001,
pagine: 19 - 26
SICI:
0959-437X(200102)11:1<19:GRBO-N>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CELL-CYCLE PROGRESSION; MAMMARY-GLAND HYPERPLASIA; TRANSGENIC MICE; C-MYC; PHOSPHOINOSITIDE 3-KINASE; S6 KINASE; CAENORHABDITIS-ELEGANS; TRANSLATIONAL CONTROL; IN-VIVO; DROSOPHILA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
81
Recensione:
Indirizzi per estratti:
Indirizzo: Prober, DA Fred Hutchinson Canc Res Ctr, Mol & Cellular Biol Program, 1100Fairview Ave N, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr 1100 Fairview Ave N Seattle WA USA 98109
Citazione:
D.A. Prober e B.A. Edgar, "Growth regulation by oncogenes - new insights from model organisms", CUR OP GEN, 11(1), 2001, pp. 19-26

Abstract

A great deal of work has focused on how oncogenes regulate the cell cycle during normal development and in cancer, yet their roles in regulating cellgrowth have been largely unexplored. Recent work in several model organisms has demonstrated that homologs of several oncogenes regulate cell growth and has suggested that some of the effects of oncogenes on the cell cycle may be a result of growth promotion. These studies have also suggested how growth and cell-cycle progression may be coupled.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 00:47:32