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Titolo:
The use of radiotelemetry in small laboratory animals: Recent advances
Autore:
Kramer, K; Kinter, L; Brockway, BP; Voss, HP; Remie, R; Van Zutphen, BLM;
Indirizzi:
Free Univ Amsterdam, Dept Safety & Environm Affairs, NL-1081 BT Amsterdam,Netherlands Free Univ Amsterdam Amsterdam Netherlands NL-1081 BT sterdam,Netherlands ASTRAZenaca LP, Wilmington, DE USA ASTRAZenaca LP Wilmington DE USAASTRAZenaca LP, Wilmington, DE USA Data Sci Int, St Paul, MN 55126 USA Data Sci Int St Paul MN USA 55126Data Sci Int, St Paul, MN 55126 USA Solvay Pharmaceut, NL-1380 DA Weesp, Netherlands Solvay Pharmaceut WeespNetherlands NL-1380 DA 380 DA Weesp, Netherlands Univ Utrecht, Fac Vet, Dept Lab Anim Sci, NL-3508 TD Utrecht, Netherlands Univ Utrecht Utrecht Netherlands NL-3508 TD 3508 TD Utrecht, Netherlands
Titolo Testata:
CONTEMPORARY TOPICS IN LABORATORY ANIMAL SCIENCE
fascicolo: 1, volume: 40, anno: 2001,
pagine: 8 - 16
SICI:
1060-0558(200101)40:1<8:TUORIS>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPONTANEOUSLY HYPERTENSIVE RATS; FREELY MOVING MICE; DOXORUBICIN-INDUCED CARDIOTOXICITY; HEART-RATE; BLOOD-PRESSURE; BODY-TEMPERATURE; CIRCADIAN-RHYTHMS; LOCOMOTOR-ACTIVITY; INDUCED HYPOTHERMIA; CORE TEMPERATURE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
106
Recensione:
Indirizzi per estratti:
Indirizzo: Kramer, K Free Univ Amsterdam, Dept Safety & Environm Affairs, Boechorststr 1, NL-1081 BT Amsterdam, Netherlands Free Univ Amsterdam Boechorststr 1 Amsterdam Netherlands NL-1081 BT
Citazione:
K. Kramer et al., "The use of radiotelemetry in small laboratory animals: Recent advances", CONT T LAB, 40(1), 2001, pp. 8-16

Abstract

Radiotelemetry provides an alternative means of obtaining physiological measurements from awake and freely moving laboratory animals, without introducing stress artifacts. For researchers, especially those in the fields of pharmacology and toxicology, the technique may provide a valuable tool for predicting the effectiveness and safety of new compounds in humans. In lightof studies described in the literature, it is concluded that there is ample evidence that the use of radiotelemetry for measuring blood pressure, cardiac activity, heart rate, body temperature, and locomotor activity in rodents has been validated sufficiently. Today, this technology is an importanttool for the stress-free collection of these physiologic data in small rodents, including mice.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 20:00:46