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Titolo:
Early serial EEG in hypoxic ischaemic encephalopathy
Autore:
Pressler, RM; Boylan, GB; Morton, M; Binnie, CD; Rennie, JM;
Indirizzi:
Univ London Kings Coll Hosp, Dept Clin Neurophysiol, London SE5 9RS, England Univ London Kings Coll Hosp London England SE5 9RS ndon SE5 9RS, England Univ London Kings Coll Hosp, Neonatal Intens Care Unit, London SE5 9RS, England Univ London Kings Coll Hosp London England SE5 9RS ndon SE5 9RS, England
Titolo Testata:
CLINICAL NEUROPHYSIOLOGY
fascicolo: 1, volume: 112, anno: 2001,
pagine: 31 - 37
SICI:
1388-2457(200101)112:1<31:ESEIHI>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
FULL-TERM; ISCHEMIC ENCEPHALOPATHY; PROGNOSTIC VALUE; NEONATAL ELECTROENCEPHALOGRAPHY; PERINATAL HYPOXIA; NEWBORN-INFANTS; ASPHYXIA; MORPHINE; PRETERM; SEIZURE;
Keywords:
neonatal EEG; hypoxic ischaemic encephalopathy; neurodevelopmental outcome;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Pressler, RM Univ London Kings Coll Hosp, Dept Clin Neurophysiol, Denmark Hill, London SE5 9RS, England Univ London Kings Coll Hosp Denmark Hill London England SE5 9RS
Citazione:
R.M. Pressler et al., "Early serial EEG in hypoxic ischaemic encephalopathy", CLIN NEU, 112(1), 2001, pp. 31-37

Abstract

Objectives: To perform early serial EEGs in infants with hypoxic ischaemicencephalopathy (HIE) and compare the findings with neurodevelopmental outcome. Methods: Nine full-term neonates with HIE had simultaneous video-EEG polygraphic studies within 8 h of birth. The EEG was repeated at 12-24 h intervals. All surviving infants had a neurodevelopmental assessment at 1 year. Results: Two infants had a normal or mildly abnormal EEG within 8 h of birth and neurodevelopmental outcome was normal. Seven infants had severely depressed background activity in the first 8 h of life. In 3 infants the EEG activity recovered within 12-24 h showing continuous activity with no or only minor abnormalities. All these infants had a normal outcome. The remaining 4 infants, who also had an initially inactive recording, subsequently developed severe background abnormalities. At follow-up, two infants had diedand the remainder developed major neurological sequelae. Conclusions: Early EEG is an excellent prognostic indicator for a favourable outcome if normal within the first 8 h of life and for a poor outcome ifthe background activity continues to be inactive or grossly abnormal beyond 8-12 h of life. However, an inactive or very depressed EEG within the first 8 h of life can be associated with good outcome if the EEG activity recovers within 12 h. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 15:38:04