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Titolo:
Resolution of organ-specific complications of human immunodeficiency virusinfection in children with use of highly active antiretroviral therapy
Autore:
Saulsbury, FT;
Indirizzi:
Univ Virginia Hlth Syst, Dept Pediat, Charlottesville, VA 22908 USA Univ Virginia Hlth Syst Charlottesville VA USA 22908 sville, VA 22908 USA
Titolo Testata:
CLINICAL INFECTIOUS DISEASES
fascicolo: 3, volume: 32, anno: 2001,
pagine: 464 - 468
SICI:
1058-4838(20010201)32:3<464:ROOCOH>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
PNEUMOCYSTIS-CARINII PNEUMONIA; NEPHROTIC SYNDROME; HIV; AIDS; DISCONTINUATION; PROPHYLAXIS; NEPHROPATHY; CYTOMEGALOVIRUS; MULTICENTER; ZIDOVUDINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Saulsbury, FT Univ Virginia Hlth Syst, Dept Pediat, Box 800386, Charlottesville, VA 22908 USA Univ Virginia Hlth Syst Box 800386 Charlottesville VA USA 22908
Citazione:
F.T. Saulsbury, "Resolution of organ-specific complications of human immunodeficiency virusinfection in children with use of highly active antiretroviral therapy", CLIN INF D, 32(3), 2001, pp. 464-468

Abstract

Opportunistic infections are a major source of morbidity and mortality in children and adults infected with human immunodeficiency virus (HIV). In addition, organ-specific complications of HIV infection, such as cardiomyopathy, nephropathy, encephalopathy, and others, contribute substantially to the morbidity and mortality associated with HIV infection. Highly active antiretroviral therapy (HAART) has produced a dramatic decline in the incidenceof opportunistic infections among patients with HIV infection. Nevertheless, there is very little information concerning the value of HAART for organ-specific complications of HIV infection. In this report, we describe 3 children with HIV infection in whom the dominant clinical manifestations were cardiomyopathy, red cell aplasia, and nephropathy. HAART produced a decrease in the HIV ribonucleic acid level, an increase in the CD4 cell count, andresolution of the organ-specific complications in all patients. These cases add to our knowledge concerning the benefits of HAART for children with HIV infection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 19:14:50