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Titolo:
Clinical characteristics of acute pulmonary thromboembolism in Japan: Results of a multicenter registry in the Japanese Society of Pulmonary EmbolismResearch
Autore:
Nakamura, M; Fujioka, H; Yamada, N; Sakuma, M; Okada, O; Nakanishi, N; Miyahara, Y; Kuriyama, T; Kunieda, T; Sugimoto, T; Nakano, T;
Indirizzi:
Mie Univ, Dept Internal Med 1, Tsu, Mie 5148507, Japan Mie Univ Tsu Mie Japan 5148507 pt Internal Med 1, Tsu, Mie 5148507, Japan Tohoku Univ, Dept Internal Med 1, Sendai, Miyagi 980, Japan Tohoku Univ Sendai Miyagi Japan 980 rnal Med 1, Sendai, Miyagi 980, Japan Chiba Univ, Dept Chest Med, Chiba, Japan Chiba Univ Chiba JapanChiba Univ, Dept Chest Med, Chiba, Japan Natl Cardiovasc Ctr, Dept Internal Med, Osaka, Japan Natl Cardiovasc Ctr Osaka Japan sc Ctr, Dept Internal Med, Osaka, Japan Nagasaki Univ, Dept Internal Med, Nagasaki 852, Japan Nagasaki Univ Nagasaki Japan 852 Dept Internal Med, Nagasaki 852, Japan Keio Univ, Ise Keio Hosp, Dept Med, Ise, Japan Keio Univ Ise JapanKeio Univ, Ise Keio Hosp, Dept Med, Ise, Japan Kanto Cent Hosp, Tokyo, Japan Kanto Cent Hosp Tokyo JapanKanto Cent Hosp, Tokyo, Japan
Titolo Testata:
CLINICAL CARDIOLOGY
fascicolo: 2, volume: 24, anno: 2001,
pagine: 132 - 138
SICI:
0160-9289(200102)24:2<132:CCOAPT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEEP-VEIN THROMBOSIS; EMBOLECTOMY; EXPERIENCE; PROGNOSIS;
Keywords:
acute pulmonary thromboembolism; anticoagulation therapy; deep venous thrombosis; thrombolytic therapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Nakamura, M Mie Univ, Dept Internal Med 1, Edobashi 2-174, Tsu, Mie 5148507, Japan Mie Univ Edobashi 2-174 Tsu Mie Japan 5148507 e 5148507, Japan
Citazione:
M. Nakamura et al., "Clinical characteristics of acute pulmonary thromboembolism in Japan: Results of a multicenter registry in the Japanese Society of Pulmonary EmbolismResearch", CLIN CARD, 24(2), 2001, pp. 132-138

Abstract

Background: Although the incidence of acute pulmonary thromboembolism (APTE) has been increasing in Japan, patient characteristics, management strategies, and outcome have nut vet been assessed in large series. Hypothesis: The present study was designed to investigate the current status of APTE in Japan. Methods: Of a total of 533 registry patients with pulmonary thromboembolism. 309 with APTE were analyzed with respect to clinical symptoms and signs,predisposing factors, diagnostic procedures, estimation of deep Venous thrombosis, treatment, and clinical course. Results: Main risk factors were recent major surgery, cancer; prolonged immobilization, and obesity; only a few patients had coagulopathy and 36% were in cardiogenic shock at presentation. The majority of registry patients underwent lung scans or pulmonary angiography; 30% were diagnosed only by lung scanning. Venous ultrasonography was used in only 34 patients, while 188patients underwent at least one diagnostic procedure for deep venous thrombosis. Thrombolysis was more frequently performed in patients with cardiogenic shock, and only a few patients received thromboembolectomy. In-hospitalmortality rate was 14%. In patients with cardiogenic shock, the mortality rate was reduced by thrombolysis. The predictors of in-hospital mortality were male gender, cardiogenic shock, cancer, and prolonged immobilization. Conclusions: The patients in this registry had almost the same findings asthose in Western patients, except for some paints that had the possibilityof demonstrating a difference between Westerners and Japanese in the development of APTE. These results can prove especially helpful in planning prospective, randomized trials that will clarify the impact of widely used treatment modalities on the outcome of patients with APTE.

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Documento generato il 03/07/20 alle ore 16:31:30