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Titolo:
A prospective cohort study of physical activity and body size in relation to prostate cancer risk (United States)
Autore:
Lee, IM; Sesso, HD; Paffenbarger, RS;
Indirizzi:
Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 th, Dept Epidemiol, Boston, MA 02115 USA Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA Brigham & Womens Hosp Boston MA USA 02115 event Med, Boston, MA 02115 USA Harvard Univ, Sch Med, Boston, MA USA Harvard Univ Boston MA USAHarvard Univ, Sch Med, Boston, MA USA Stanford Univ, Sch Med, Div Epidemiol, Stanford, CA USA Stanford Univ Stanford CA USA , Sch Med, Div Epidemiol, Stanford, CA USA
Titolo Testata:
CANCER CAUSES & CONTROL
fascicolo: 2, volume: 12, anno: 2001,
pagine: 187 - 193
SICI:
0957-5243(200102)12:2<187:APCSOP>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
HORMONE-BINDING GLOBULIN; COLLEGE ALUMNI; GROWTH-HORMONE; HEALTH; POPULATION; OBESITY; INSULIN; QUESTIONNAIRE; PREVENTION; DISEASE;
Keywords:
anthropometry; cohort study; obesity; physical activity; prostate cancer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, IM Harvard Univ, Sch Publ Hlth, Dept Epidemiol, 677 Huntington Ave, Boston, MA 02115 USA Harvard Univ 677 Huntington Ave Boston MA USA 02115 , MA 02115 USA
Citazione:
I.M. Lee et al., "A prospective cohort study of physical activity and body size in relation to prostate cancer risk (United States)", CANC CAUSE, 12(2), 2001, pp. 187-193

Abstract

Objectives: To examine the associations of physical activity and body sizewith risk of prostate cancer. Methods: At baseline in 1988, 8922 men (mean age 67 years) completed a health questionnaire which included information on physical activity, body weight, and waist girth. In a subgroup (74% of men), physical activity data also had been provided in 1962 or 1966 and again in 1977. Additionally, body weight measured at age 18 was available for 92% of men. During follow-up from 1988 through 1993, 439 men developed prostate cancer. Results: In multivariate analyses that accounted for potential confounders, the RRs (95% CI) for < 4200, 4200-8399, 8400-12,599, and greater than or equal to 12,600 kJ/week of physical activity at baseline were 1.00 (referent), 1.13 (0.84-1.52), 0.96 (0.68-1.35), and 1.04 (0.79-1.38), respectively. For body mass indexes (BMI) of < 22.5, 22.5-24.9, 25.0-27.4, and greater than or equal to 27.5 kg/m(2) at baseline, corresponding results were 1.00 (referent), 1.27 (0.94-1.71), 1.26 (0.92-1.72), and 1.02 (0.68-1.53), respectively. For waist girths of less than or equal to 86.4, 86.5-91.4, 91.5-96.5, and > 96.5 cm, they were 1.00 (referent), 1.30 (0.96-1.76), 1.31 (0.96-1.80), and 1.19 (0.85-1.65), respectively. Combining physical activity measures from the past, or examining vigorous activities only, did not yield anysignificant associations. BMI at age 18 also was not related to risk. Conclusion: These findings do not support a role of physical activity or body weight in prostate cancer etiology.

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Documento generato il 07/08/20 alle ore 00:47:55