Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Diet and nutrition as risk factors for multiple myeloma among blacks and whites in the United States
Autore:
Brown, LM; Gridley, G; Pottern, LM; Baris, D; Swanson, CA; Silverman, DT; Hayes, RB; Greenberg, RS; Swanson, GM; Schoenberg, JB; Schwartz, AG; Fraumeni, JF;
Indirizzi:
NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA NCI BethesdaMD USA 20892 Epidemiol & Genet, NIH, Bethesda, MD 20892 USA Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA USA Emory Univ Atlanta GA USA y Univ, Rollins Sch Publ Hlth, Atlanta, GA USA Michigan Canc Fdn, Detroit, MI 48201 USA Michigan Canc Fdn Detroit MI USA48201 an Canc Fdn, Detroit, MI 48201 USA New Jersey State Dept Hlth, Trenton, NJ 08625 USA New Jersey State Dept Hlth Trenton NJ USA 08625 th, Trenton, NJ 08625 USA
Titolo Testata:
CANCER CAUSES & CONTROL
fascicolo: 2, volume: 12, anno: 2001,
pagine: 117 - 125
SICI:
0957-5243(200102)12:2<117:DANARF>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
FATTY-ACIDS; IMMUNE-SYSTEM; CANCER RISK; QUESTIONNAIRE; OBESITY;
Keywords:
case-control studies; diet; multiple myeloma; obesity; vitamin supplements;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Brown, LM NCI, Div Canc Epidemiol & Genet, NIH, Execut Plaza S,Room 8026,6120 ExecutBlvd,MSC 72, Bethesda, MD 20892 USA NCI Execut Plaza S,Room 8026,6120 Execut Blvd,MSC 72 Bethesda MD USA 20892
Citazione:
L.M. Brown et al., "Diet and nutrition as risk factors for multiple myeloma among blacks and whites in the United States", CANC CAUSE, 12(2), 2001, pp. 117-125

Abstract

Objectives: To explore whether dietary factors contribute to the risk of multiple myeloma and the two-fold higher incidence among blacks compared to whites in the United States. Methods: Data from a food-frequency questionnaire were analyzed for 346 white and 193 black subjects with multiple myeloma, and 1086 white and 903 black controls who participated in a population-based case-control study of multiple myeloma in three areas of the United States. Results: Elevated risks were associated with obese vs. normal weight (OR =1.9, 95% confidence interval (CI) = 1.2-3.1 for whites and OR = 1.5, 95% CI = 0.9-2.4 for blacks), while the frequency of obesity was greater for black than white controls. Reduced risks were related to frequent intake of cruciferous vegetables (OR = 0.7, 95% CI = 0.6-0.99) and fish (OR = 0.7, 95% CI = 0.5-0.9) in both races combined, and to vitamin C supplements in whites (OR = 0.6, 95% CI = 0.5-0.9) and blacks (OR = 0.8, 95% CI = 0.5-1.4), with the frequency of vitamin supplement use being greater for white than black controls. However, frequent intake of vitamin C from food and supplementscombined was associated with a protective effect in whites (OR = 0.6, 95% CI = 0.4-0.9), but not blacks (OR = 1.2, 95% CI = 0.8-2.1). Conclusions: The greater use of vitamin C supplements by whites and the higher frequency of obesity among blacks may explain part of the higher incidence of multiple myeloma among blacks compared to whites in the United States. In addition, the increasing prevalence of obesity may have contributed to the upward trend in the incidence of multiple myeloma during recent decades.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 02:32:23