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Titolo:
Bone mineral metabolism after total gastrectomy
Autore:
Heiskanen, JT; Kroger, H; Paakkonen, M; Parviainen, MT; Lamberg-Allardt, C; Alhava, E;
Indirizzi:
N Carelian Cent Hosp, Dept Surg, Joensuu, Finland N Carelian Cent Hosp Joensuu Finland Hosp, Dept Surg, Joensuu, Finland Kuopio Univ Hosp, Dept Surg, SF-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland SF-70210 Surg, SF-70210 Kuopio, Finland Kuopio Univ Hosp, Dept Clin Chem, SF-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland SF-70210 Chem, SF-70210 Kuopio, Finland Univ Helsinki, Dept Appl Chem & Microbiol, Helsinki, Finland Univ Helsinki Helsinki Finland Appl Chem & Microbiol, Helsinki, Finland
Titolo Testata:
BONE
fascicolo: 1, volume: 28, anno: 2001,
pagine: 123 - 127
SICI:
8756-3282(200101)28:1<123:BMMATG>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
X-RAY ABSORPTIOMETRY; POSTGASTRECTOMY OSTEOPOROSIS; DISEASE; WOMEN; SERUM; RADIOIMMUNOASSAY; DENSITY; MASS; RISK; MEN;
Keywords:
total gastrectomy; gastric surgery; bone metabolism; bone mineral density (BMD); osteoporosis; dual-energy x-ray absorptiometry (DXA);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Heiskanen, JT Kirugian Osasto, Pohjois Karjalan Keskussairaala, FIN-80210 Joensuu, Finland Kirugian Osasto Joensuu Finland FIN-80210 Joensuu, Finland
Citazione:
J.T. Heiskanen et al., "Bone mineral metabolism after total gastrectomy", BONE, 28(1), 2001, pp. 123-127

Abstract

Gastric surgery is mostly needed for treatment of gastric malignancy. To investigate the effect of total gastrectomy on bone mineral density (BMD) and bone mineral metabolism we evaluated 18 patients after total gastrectomy. Mean interval since operation was 71 +/- 20 months. BMD results were compared with age- and gender-matched controls (n = 46) and also expressed as T and Z scores, Bone mineral density measured by dual-energy X-ray absorptiometry (DXA) was found to be significantly lower in patients after total gastrectomy compared with healthy controls in the lumbar spine (p = 0.017 for women,p = 0.002 for men), femoral neck (p 0.004 for women, p = 0.001 for men), Ward's triangle (p 0.031 for women,p = 0.003 for men), and greater trochanter (p = 0.001 for women, p = 0.001 for men). Z scores for lumbar spine, femoral neck, Ward's triangle, and greater trochanter were -0.83, -1.54, -1.02, and -1.19, respectively. Biochemical measurements correlated poorly with BMD and were found to be of lesser value in diagnosing reduced bone massas well as in differential diagnosis of etiology of osteopenia, The results of our study show the deleterious effect of total gastrectomy on bone mineral status and suggest an increased fracture risk in these patients, (C) 2001 by Elsevier Science Inc, All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 15:48:51