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Titolo:
Complete nucleotide sequence and analysis of a novel human papillomavirus (HPV 84) genome cloned by an overlapping PCR method
Autore:
Terai, M; Burk, RD;
Indirizzi:
Albert Einstein Coll Med, Dept Microbiol & Immunol, Ctr Comprehens Canc, Bronx, NY 10461 USA Albert Einstein Coll Med Bronx NY USA 10461 ens Canc, Bronx, NY 10461 USA Albert Einstein Coll Med, Dept Pediat, Ctr Comprehens Canc, Bronx, NY 10461 USA Albert Einstein Coll Med Bronx NY USA 10461 ens Canc, Bronx, NY 10461 USA Albert Einstein Coll Med, Dept Epidemiol & Social Med, Ctr Comprehens Canc, Bronx, NY 10461 USA Albert Einstein Coll Med Bronx NY USA 10461 ens Canc, Bronx, NY 10461 USA
Titolo Testata:
VIROLOGY
fascicolo: 1, volume: 279, anno: 2001,
pagine: 109 - 115
SICI:
0042-6822(20010105)279:1<109:CNSAAO>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
RISK-FACTORS; CERVICAL CANCERS; E6/E7 PROMOTER; BINDING-SITES; YOUNG-WOMEN; INFECTION; TRANSCRIPTION; EPIDEMIOLOGY; REPLICATION; PREVALENCE;
Keywords:
HPV; human papillomavirus; cervical cancer; STD; sexually transmitted disease; overlapping PCR; phylogeny;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Burk, RD Albert Einstein Coll Med, Dept Microbiol & Immunol, Ctr Comprehens Canc, 1300 Morris Pk Ave, Bronx, NY 10461 USA Albert Einstein Coll Med 1300 Morris Pk Ave Bronx NY USA 10461 SA
Citazione:
M. Terai e R.D. Burk, "Complete nucleotide sequence and analysis of a novel human papillomavirus (HPV 84) genome cloned by an overlapping PCR method", VIROLOGY, 279(1), 2001, pp. 109-115

Abstract

Molecular diagnosis of human papillomaviruses (HPVs) in cervicovaginal samples reveals a plethora of known and novel HPV genomes. We describe the useof an overlapping PCR method to clone and analyze the complete genome of HPV 84 from cervicovaginal cells obtained from a 21-year-old Caucasian female with a normal nap smear. The 7948-bp complete nucleotide sequence of HPV 84 was determined from five overlapping PCR products by sequence walking. ABLAST homology search demonstrated that HPV 84 was most closely related toHPV 61 (89%), HPV 72 (86%), and HPV 83 (85%) by nucleotide sequence analysis of the Ll open reading frame, placing it in the HPV genome homology group As. Previously, this virus had been identified as Pap155. Based on extensive epidemiological data, HPV 84 is a highly prevalent genital papillomavirus primarily detected in normal and HIV-infected women, (C) 2001 academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/21 alle ore 07:34:48